NCT04630574Completed
Characterization and Quantification of Motor Speech Disorders in Huntington's Disease: Identification of Acoustic Markers
Source: ClinicalTrials.gov · Last updated 20 Feb 2024
Brief summary (registry, in English)
The study proposes to identify deviant speech dimensions in patients with HD at presymptomatic and declared stages of the disease, compared to healthy subjects, using the computerized MonPaGe speech protocol. This tool is based on a multidimensional and quantified assessment of voice and speech, by a set of targeted acoustic and perceptual criteria.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 150 (actual)
- First submitted
- 1 Nov 2020
- Start date
- 23 Feb 2021
- Primary completion date
- 5 Feb 2024
- Lead sponsor
- University Hospital, Bordeaux
- Diseases
- Huntington's disease
- NCT number
- NCT04630574
What you commit to
- Study type: Observational
- Participants enrolled: 150
- From 23 Feb 2021 to the primary completion date, 5 Feb 2024
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Huntington's disease patients with severe dysarthria (BECD score\> 16), acoustic analysis not being possible on unintelligible speech
Other
- patients placed under the protection of justice
Who the study is looking for
- major patients
- francophone patients
- Huntington's disease carriers confirmed by molecular biological analysis
- carriers of pre-symptomatic Huntington's disease: Total Motor Score of the Unified Huntington's Disease Rating Scale \<5
- carriers of Huntington's disease at a declared stage: Total Motor Score of the Unified Huntington's Disease Rating Scale ≥ 5
- followed in the Competence Center Huntington's disease Bordeaux Hospital or in the Reference Center Huntington's disease Henri Mondor Hospital of Créteil
- affiliates or beneficiaries of a social security scheme
- Finally, a free, informed and express consent of the patient must be collected.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hopital Henri Mondor Coordinator of this site? Confirm its status | Créteil | France | Unknown status |
| Centre Hospitalier Universitaire De Bordeaux Coordinator of this site? Confirm its status | Talence | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.