Exploring the Immunology of Sarcoidosis
Key facts
- Who runs it
- Hull University Teaching Hospitals NHS Trust
- Where
- United Kingdom1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Completed
- People taking part
- 9 people enrolled
- Started
- 11 Nov 2019
- Ended
- 31 Dec 2023
- Type of study
- Observational
- Treatments tested
- This is a non-interventional study
- Record updated
- 2 October 2024
Who can take part
- Age
- 18 years to 85 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 5 criteriaShow less
Who can take part
- Males or females, of any race, between 18 and 85 years of age, inclusive
- Able to provide written informed consent
- Clinician diagnosis of sarcoidosis
- Treatment-naïve or receiving immunomodulatory therapy
Who cannot take part
- Evidence of acute bacterial infection or other condition likely in the opinion of the investigator to significantly impact results of blood assays
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
In sarcoidosis, over activity of parts of the immune system drives the accumulation of granulomas (collections of immune cells) in affected parts of the body. To facilitate development of effective and safe treatment options in the future it will be vital to understand how and why the immune system becomes over active. The aim of this research is to work towards this goal by studying cells of the immune system and the molecular pathways inside these cells that control how they behave. This will be achieved by analysing patterns of proteins and RNA (the code used to tell cells which proteins to produce) in immune cells present in blood samples and tissue biopsies from people with sarcoidosis.
Treatments tested
- This is a non-interventional study
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Record updated
- 2 October 2024