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Preventing the Recurrence of Acute Pancreatitis by Alcohol and Smoking Cessation

Key facts

Who runs it
University of Pecs
Where
Hungary1 site in 1 countryChoose a country to see its sites
Trial code
Status
Recruiting
People taking part
364 people, planned
Started
1 Mar 2022
Expected to end
30 Jun 2028
Type of study
Interventional, 2 groupsOne group gets an existing treatment, for comparison.
Treatments tested
  • Standard intervention only
  • Standard intervention plus repeated intervention
Record updated
26 April 2023

Who can take part

Age
18 years to 80 years
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

Show all 13 criteriaShow less

Who can take part

  • Patient hospitalized with alcohol-induced AP (defined by the revised Atlanta criteria 38)
  • Every day smoker (defined as an adult patient who smoked at least 100 cigarettes in his or her lifetime, and now smokes on a daily basis; as per the CDC definition), with at least 1-year history of smoking
  • Aged 18-80 years
  • Provided written informed consent
  • Willing to participate in the intervention in every three months

Who cannot take part

  • Currently taking part in a smoking cessation program
  • Possible etiologies for AP other than alcohol (eg. gallstone-related, hypertriglyceridemia above 11.5 mM 40-42, hypercalcemia, viral infection) if the etiological cannot be terminated during the index admission (lack of same admission cholecystectomy, familiar hypertrygliceridemia) and cases with combined etiological factors will be excluded
  • Untreated, decompensated or severe mMajor psychiatric illnesses (e.g. schizophrenia, bipolar disorder, dementia)
  • Undergoing active or palliative treatment for malignancy
  • Pregnancy, breastfeeding
  • Life expectancy is less than two years
  • Didn't agreed to participate
  • Other

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 80 years old?

This trial has no sites in United States.

It has sites in one country. Choose a country to see its sites.

About the trial

What the trial wants to find out

Recurrence of acute pancreatitis (AP) is often facilitated by regular alcohol consumption and smoking. An applied lifestyle intervention focusing on the cessation of alcohol consumption and smoking might prevent the recurrence of AP. REAPPEAR Study is a randomized controlled trial and a cohort study focusing on the efficacy of the lifestyle intervention and the effect of quitting alcohol and smoking respectively.

The 2 groups in the trial

  • Standard intervention plus repeated interventionExisting treatment, for comparison

    Patients randomized to the standard intervention plus repeated intervention arm

  • Standard intervention onlyExisting treatment, for comparison

    Patients randomized to the standard intervention only arm

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Recurrent Acute Pancreatitis Prevention by the Elimination of Alcohol and Cigarette Smoking (REAPPEAR): Protocol of a Randomized Controlled Trial and a Cohort Study
Fit questions
Built from NCT04647097, who can take part
Record updated
26 April 2023