NCT04649034Completed
Intraventricular Stasis In Cardiovascular Disease
Personalizing The Risk Of Stroke And Silent Brain Infarct In Cardiovascular Disease
Source: ClinicalTrials.gov · Last updated 15 Sept 2025
Brief summary (registry, in English)
This study is designed to quantify the ventricular stasis in patients with different forms of cardiomyopathy and at risk of stroke (ischemic, non-ischemic dilated cardiomyopathy and hypertrophic cardiomyopathy) by post-processing of 2D color Doppler echocardiography and phase contrast-magnetic resonance images in order to establish the relationship between quantitative variables of intraventricular stasis and the prevalence of silent embolic events and/or intraventricular mural thrombosis.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 258 (actual)
- First submitted
- 24 Nov 2020
- Start date
- 24 Nov 2020
- Primary completion date
- 31 Dec 2024
- Lead sponsor
- Hospital General Universitario Gregorio Marañon
- Diseases
- Hypertrophic cardiomyopathy, Stroke
- NCT number
- NCT04649034
What you commit to
- Study type: Observational
- Participants enrolled: 258
- From 24 Nov 2020 to the primary completion date, 31 Dec 2024
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior history of significant carotid disease with stenosis greater than 50%.
- Full anticoagulation therapy prior to admission or indication of anticoagulation.
Other illness
- Hemodinamically significant heart valve disease or prosthetic heart valves.
- Pro-thrombotic disorders (active oncology disease, coagulation disorders…)
Other
- Implantable defibrillation or stimulation devices not compatible with MRI.
- Claustrophobia.
- Persistent of paroxysmal atrial fibrillation (AF).
Who the study is looking for
- Patients over 18 years of age.
- Sinus rhythm.
- Meet one of the following criteria:
- Diagnosis of non ischemic DCM and ejection fraction (EF) of LV less than 45%
- Diagnosis of ischemic DCM and ejection fraction (EF) of LV less than 45%
- Diagnosis of hypertrofic myocardiophathy and ejection fraction (EF) of LV less than 55% or apical aneurism diagnosed in an image test.
Age in the registry: 18 years to 100 years · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital Clinic de Barcelona Coordinator of this site? Confirm its status | Barcelona | Spain | Unknown status |
| Hospital General Universitario Gregorio Marañón Coordinator of this site? Confirm its status | Madrid | Spain | Unknown status |
| Hospital Universitario Clinico de Salamanca Coordinator of this site? Confirm its status | Salamanca | Spain | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.