Frontlight ResearchEarly access
CompletedPhase 3
Dexamethasone for Post Uterine Artery Embolization Pain
Key facts
- Who runs it
- University of Miami
- Where
- Miami, United StatesSee the site
- Trial code
- Status
- Completed
- Phase
- Phase 3
- People taking part
- 42 people enrolled
- Started
- 25 Jan 2021
- Ended
- 4 Dec 2024
- Type of study
- Interventional, 2 groupsOne group gets a placebo (a dummy treatment), for comparison.
- Treatments tested
- Dexamethasone
- Saline
- Record updated
- 7 January 2026
Who can take part
- Age
- 20 years to 50 years
- Sex
- Women only
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 8 criteriaShow less
Who can take part
- Women who meet criteria to undergo uterine fibroid embolization for symptomatic fibroids
Who cannot take part
- Previous documented allergy to dexamethasone
- Those currently taking daily steroids for any reason
- Those with diabetes or deemed to be pre-diabetic
- Currently pregnant or actively attempting to conceive
- Those deemed mentally impaired to make their own medical decisions
- Those with contraindications for angiography
- Prisoners
Where in United States
- Sylvester Comprehensive Cancer Center*Miami, United States
About the trial
What the trial wants to find out
The purpose of this research is to investigate if administration steroids (anti-inflammatory medication) via the uterine arteries during uterine fibroid embolization (A non surgical procedure for treating uterine fibroids by blocking their blood supply) can help reduce the pain, nausea, vomiting, and general feeling of weakness following the procedure.
The 2 groups in the trial
- Dexamethasone ArmTreatment being tested
A total of 5mg dexamethasone will be administered into each uterine artery (10mg total) prior to uterine artery embolization.
Treatment: Dexamethasone
- Saline ArmPlacebo, for comparison
A volume of normal saline, equal to the total volume delivered in the Dexamethasone Arm, will be administered into each uterine artery prior to uterine artery embolization.
Treatment: Saline
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Intra-Arterial Dexamethasone for the Alleviation of Pain and Postembolization Syndrome Following Uterine Artery Embolization
- Record updated
- 7 January 2026