MRI and implanted monitor to predict atrial fibrillation after heart bypass surgery
Studies heart imaging and an implanted monitor in adults having bypass surgery.
Plain-language title generated from the registry record
Registry title: Multiparametric MRI Assessment of Atrial Heart Disease as a Predictor of Atrial Fibrillation After Myocardial Revascularization Surgery
Key facts
- Where
- Saint-Etienne, FranceSee the site
Where in France
- CHU Saint-EtienneSaint-Etienne, FranceNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Centre Hospitalier Universitaire de Saint Etienne
- Trial code
- NCT04657835
- Record updated
- 7 October 2026
- Original description
Postoperative atrial fibrillation (POAF) occurs in 20-40% of patients undergoing coronary artery bypass grafting (CABG) and is a marker of atrial vulnerability. It is strongly associated with AF recurrence, stroke, and cardiovascular mortality. It presents risk factors with atrial heart disease.Read full original descriptionShow less
Multiparametric MRI Assessment of Atrial Heart Disease as a Predictor of Atrial Fibrillation After Myocardial Revascularization Surgery
Postoperative atrial fibrillation (POAF) occurs in 20-40% of patients undergoing coronary artery bypass grafting (CABG) and is a marker of atrial vulnerability. It is strongly associated with AF recurrence, stroke, and cardiovascular mortality. It presents risk factors with atrial heart disease.
The latter refers to all structural, electrical, and mechanical alterations of the atrium that create a substrate conducive to AF.
Multiparametric cardiac MRI is currently the most comprehensive test for assessing atrial heart disease, thanks to its structural and functional analysis (atrial fibrosis, atrial strain, intracavitary 4D flow). However, to date, no prospective study has evaluated these parameters as predictors of AF recurrence after CAP. At the same time, an implantable Holter monitor will be used to enable detailed and continuous detection of recurrence episodes, overcoming the limitations of conventional monitoring strategies. By combining multiparametric imaging, histological analysis, and continuous monitoring for the first time, this study proposes a paradigm shift in the assessment of postoperative AF: moving from a descriptive and ad hoc approach to a mechanistic, integrative, and predictive approach.
Inclusion: Age ≥ 18 years; Indication for surgical myocardial revascularization by isolated coronary artery bypass grafting, to be performed in the cardiac surgery department of Saint-Étienne University Hospital; Patient affiliated with or entitled to social security coverage; Patient who has received informed information about the study and has co-signed, with the investigator, a consent form to participate in the study.
Exclusion: Concomitant indication for valve surgery or other associated cardiac intervention; Contraindication related to cardiac MRI; Documented history of atrial fibrillation; Contraindication related to ILR implantation; Inability to understand French; Patient refusal to participate in the study and/or inability to express consent or sign the informed consent form; Patient subject to legal protection measures.