Following adults with obstructive sleep apnea over time in Hong Kong

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults who may have obstructive sleep apnea, where the airway keeps closing during sleep. It follows them over time to study heart risk and memory and thinking decline.

Age

18 years or older

Sex

All sexes

Disease stage

Suspected obstructive sleep apnea syndrome, not yet treated.

Earlier treatment

People whose sleep apnea has already been treated cannot join.

Main reasons for not taking part

• Sleep apnea already treated
• Short expected lifespan due to an illness not related to sleep apnea
• HIV, advanced kidney disease or uncontrolled cancer
• Alcohol or drug abuse on record within 1 year before joining
• Not able to speak, read and understand Chinese or English, or to answer questions and follow instructions

The registry criteria, word for word

What the trial wants to find out

Obstructive sleep apnea syndrome (OSAS) is a common disorder with prevalence rates of at least 4% among the middle-aged male Caucasians and Hong Kong (HK) Chinese populations. It is characterized by repetitive episodes of upper airway obstruction, causing intermittent hypoxia, sleep fragmentation, disabling daytime sleepiness, impaired cognitive function and poor health status. OSAS patients are at increased risks of non-fatal and fatal cardiovascular morbidity and mortality including sudden death, in addition to being more prone to road traffic accidents. However, there is no long term follow up of patients with OSAS on the incidence of cardiovascular disease, compliance on the therapy and the impact of the quality of life. The study is aimed to carry out a prospective observational study assessing the role of OSAS as a possible cause of increased cardiovascular risk and cognitive decline.