NCT04663230Completed
Right Atrial Fibrosis in Pulmonary Hypertension
Source: ClinicalTrials.gov · Last updated 17 May 2024
Brief summary (registry, in English)
The study aim to assess right atrial (RA) remodeling, in terms of RA fibrosis, in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension patients. This will be investigated in detail with in-depth cardiac magnet resonance imaging (CMRI). A cohort with exclusion of pulmonary hypertension which underwent CMRI due to dyspnoe of unkown reason will be the control group.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 40 (actual)
- First submitted
- 9 Nov 2020
- Start date
- 30 Apr 2021
- Primary completion date
- 30 Nov 2022
- Lead sponsor
- University of Giessen
- NCT number
- NCT04663230
What you commit to
- Study type: Observational
- Participants enrolled: 40
- From 30 Apr 2021 to the primary completion date, 30 Nov 2022
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Metallic implants
Other illness
- Other etiologic groups of pulmonary hypertension (WHO group 2, 3, 5)
- Patients with congenital heart disease
- Clinical relevant left heart disease
- History of major cardiac surgery
- Other severe disease with a life expectancy below 12 month
- Any known factor or disease that might interfere with treatment compliance, study conduct, or interpretation of results
- Inability to perform a cardiac magnetic resonance imaging (claustrophobia or similar)
Lab values
- Severe renal impairment (eGFR \< 30 ml/min)
Other
- Atrial septal defects
- Atrial fibrillation / Atrial flutter
- Ablations of the right atrium
- Atrial occlude
- Pacemakers
- Pregnancy
- Intolerance to a contrast agent containing gadolinium
Who the study is looking for
- Confirmed diagnosis of pulmonary arterial hypertension, WHO group 1 or chronic thromboembolic pulmonary hypertension, group 4
- Invasive exclusion of pulmonary hypertension
- Age ≥ 18 years
- Signed informed consent
- planned right heart catheterization based on clinical grounds
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Kerckhoff-Klinik Coordinator of this site? Confirm its status | Bad Nauheim | Germany | Unknown status |
| University of Giessen Coordinator of this site? Confirm its status | Giessen | Germany | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.