Heat treatment of benign thyroid nodule during thyroid cancer surgery
Tests heat ablation of a benign thyroid nodule during lobectomy in adults with thyroid cancer.
Plain-language title generated from the registry record
Registry title: Function Integrity of Neck Anatomy in Thyroid Surgery
Key facts
- Where
- Wuhan, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT04666103, who can take part
Where in China
- Zhongnan Hospital of Wuhan UniversityWuhan, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Wuhan University
- Trial code
- NCT04666103
- Record updated
- 14 December 2020
- Original description
Recent trends in the management of patients with low-risk papillary thyroid carcinoma who have a nonsuspicious or cytologically benign contralateral nodule call into question the need for routine total thyroidectomy. Although the lobectomy for the unilateral thyroid cancer with contralateral benign nodules is sufficient treatment, some of the patients might suffer from the anxiety of the residual benign thyroid nodule and tend to choose total thyroidectomy, which might be overtreatment.Read full original descriptionShow less
Preserving Function Integrity of Neck Anatomy in Thyroid Surgery: A Randomized Clinical Trial
Recent trends in the management of patients with low-risk papillary thyroid carcinoma who have a nonsuspicious or cytologically benign contralateral nodule call into question the need for routine total thyroidectomy. Although the lobectomy for the unilateral thyroid cancer with contralateral benign nodules is sufficient treatment, some of the patients might suffer from the anxiety of the residual benign thyroid nodule and tend to choose total thyroidectomy, which might be overtreatment.
Thermal ablation has been proven to be effective in achieving nodule shrinkage and being also free from major complications. In our institution, intraoperative RFA was a proposed alternative strategy to treat the contralateral benign nodules after the thyroid lobectomy for the malignant lobe, which was found to have a better quality of life on anxiety, physiological health, social family, psychological and sensory mentions with a considerable complication rate.
Inclusion: Patients diagnosed with unilateral thyroid carcinoma and contralateral benign nodule confirmed by preoperative ultrasound-guided fine-needle aspiration cytology; Patients with contralateral nodules ≤ 20mm and located in the thyroid gland; Patients with clinical node-negative cervical compartment at palpation and neck ultrasound.
Exclusion: Previous history of neck surgery; Previous history of neck radiation therapy.