NCT04680130Enrolling by invitation
Clinico-Pathologic-Genetic-Imaging Study of Neurodegenerative and Related Disorders
Source: ClinicalTrials.gov · Last updated 21 Nov 2025
Brief summary (registry, in English)
The investigators aim to learn more about symptoms suggestive of a neurodegenerative process.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 500 (estimated)
- First submitted
- 3 Nov 2020
- Start date
- 1 Nov 2020
- Primary completion date
- Nov 2050
- Lead sponsor
- Mayo Clinic
- Diseases
- Frontotemporal dementia, Parkinson disease
- NCT number
- NCT04680130
What you commit to
- Study type: Observational
- Planned participants: 500
- From 1 Nov 2020 to the primary completion date, Nov 2050
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Participants will be excluded if they have any concurrent illnesses that could account for all of their symptoms, such as traumatic brain injury, encephalitis, strokes or developmental syndromes
- Participants will be excluded if they are medically unstable or are on medications that might affect brain structure or metabolism (e.g. chemotherapy)
Other illness
- Participants will be excluded if they have any of the following genetic conditions which can increase the chance of cancer: Cowden disease, Lynch syndrome, Hypogammaglobulinemia, Wiskott-Aldrich syndrome and Down's syndrome
- Participants will be excluded if MRI is contraindicated (metal in head, cardiac pace maker, etc), if there is severe claustrophobia, if there are conditions that may confound brain imaging studies (e.g. structural abnormalities, including subdural hematoma, intracranial neoplasm or large cortical infarcts)
Other
- Women that are pregnant or post-partum and breast-feeding will be excluded
Who the study is looking for
- All participants will be over the age of 21
- Have symptoms suggestive of a neurodegenerative and/or related disorder
Age in the registry: 21 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mayo Clinic Coordinator of this site? Confirm its status | Rochester | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.