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Remote Speech Therapy Compared With Clinic Therapy for Aphasia After Stroke

Compares remote video speech therapy with in-clinic therapy for language loss after stroke.

Plain-language title generated from the registry record
Registry title: Telerehabilitation for Aphasia (TERRA)

Key facts

Where
Columbia, United StatesSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 21 and 80 years old?

Source: NCT04682223, who can take part

Where in United States

  • University of South Carolina Aphasia LabColumbia, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
University of South Carolina
Trial code
NCT04682223
Record updated
2 April 2026
Original description
Speech-language therapy is generally found to be helpful in the rehabilitation of aphasia. However, not all patients with aphasia have access to adequate treatment to maximize their recovery. The goal of this project is to compare the efficacy of telerehabilitation or Aphasia Remote Therapy (ART) to the more traditional In-Clinic Therapy (I-CT).Read full original descriptionShow less

Center for the Study of Aphasia Recovery (C-STAR): Telerehabilitation for Aphasia (TERRA)

Speech-language therapy is generally found to be helpful in the rehabilitation of aphasia. However, not all patients with aphasia have access to adequate treatment to maximize their recovery. The goal of this project is to compare the efficacy of telerehabilitation or Aphasia Remote Therapy (ART) to the more traditional In-Clinic Therapy (I-CT).

Inclusion: Participants must have sustained a left hemisphere ischemic or hemorrhagic stroke at least 12 months prior to enrollment; Participants must primarily speak English for at least the past 20 years; Participants must be capable of giving informed consent or indicating another to provide informed consent; Participants must be between 21-80 years of age; Participants must be magnetic resonance imaging (MRI) compatible (e.g., no metal implants, not claustrophobic) on a 3-Tesla (3T) scanner.

Exclusion: Participants must not have previous neurological disease affecting the brain (e.g. history of traumatic brain injury); Participants must not have severely limited speech production (severe unintelligibility) and/or auditory comprehension that interferes with adequate participation in the therapy provided (i.e., WAB-R Spontaneous Speech rating scale score of 0-1 or WAB-R Comprehension score of 0-1); Participants must not have a history of stroke to the right hemisphere of the brain; Participants must not have a bilateral, cerebellar or brainstem stroke; Participants must not have anything that makes them be 3T MRI incompatible; Insufficient intelligible speech to provide accurate responses with discourse/naming.

ClinicalTrials.gov NCT04682223