Registry Tracking Outcomes in People With Cardiogenic Shock
Collects records of people with cardiogenic shock treated with drugs or devices.
Key facts
- Who runs it
- Tufts Medical Center
- Where
- Boston, Chicago, Dallas, Falls Church, Galveston, Hackensack, Houston, New York, Pittsburgh, Portland, Seattle, and Weston, United StatesSee the 16 sites
- Trial code
- Registry title
- Cardiogenic Shock Working Group Registry
- Status
- Recruiting
- People taking part
- 20,000 people, planned
- Started
- 4 Dec 2017
- Expected to end
- Dec 2027
- Type of study
- Observational
- Treatments tested
- Vasopressor
- Inotrope
- Acute Mechanical Circulatory Support Devices
- Record updated
- 27 October 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The registry is looking for adults who have cardiogenic shock, a state where the heart cannot pump enough blood. Data are collected from their medical records and follow-up phone calls.
- Age
- 18 Years and older
- Sex
- All sexes can join.
- Disease stage
- Cardiogenic shock, meaning at least 2 of these at the same time during the hospital stay: Cardiac Index < 2.2, PAPI < 1.0, Cardiac Power Output ≤ 0.6, MAP < 60mmHg or a >30mmHg drop in MAP from baseline, SBP < 90mmHg or a >30mmHg drop in SBP from baseline, or Pulse > 100. Or needing a mechanical heart support device, vasopressor or inotrope drug to keep these values above target.
- Earlier treatment
- People who had heart surgery can join only 72 hours after their surgery.
Main reasons for not taking part
- Not having cardiogenic shock
- Heart surgery less than 72 hours ago
The registry criteria, word for word
Show all 3 criteriaShow less
Who can take part
- Patients must have cardiogenic shock; Cardiogenic shock is defined by at least one of the two categories below:
- At least 2 of the following concurrently at any point during the index hospitalization:; Cardiac Index < 2.2; PAPI < 1.0; Cardiac Power Output ≤ 0.6; MAP < 60mmHg or a >30mmHg drop in MAP from baseline; SBP < 90mmHg or a >30mmHg drop in SBP from baseline; Pulse > 100
- Require at least one acute mechanical circulatory support device, vasopressor or inotrope to maintain values above the above target; Post-cardiotomy patients must meet the inclusion criteria 72 hours after their surgery to be included in this registry
Where in United States
- Beth Israel Deaconess Medical CenterBoston, United StatesContact: Arthur R GaranTaking people
- Tufts Medical CenterBoston, United StatesContact: Navin K Kapur, MDTaking people
- Northwestern MedicineChicago, United StatesContact: Esther Vorovich, MDTaking people
- University of ChicagoChicago, United StatesContact: Sandeep Nathan, MDTaking people
- Baylor Scott & White Advanced Heart Failure ClinicDallas, United StatesContact: Detlef Wencker, MDTaking people
- Inova Health SystemFalls Church, United StatesContact: Shashank Sinha, MD, MScTaking people
- University of Texas Medical BranchGalveston, United StatesContact: Wissam Khalife, MDTaking people
- Hackensack Meridian HealthHackensack, United StatesContact: Haroon Faraz, MDTaking people
- Houston Methodist HospitalHouston, United StatesContact: : Ju H Kim, MDTaking people
- Columbia University Irving Medical CenterNew York, United StatesContact: Justin Fried, MDTaking people
- Allegheny General HospitalPittsburgh, United StatesContact: Manreet Kanwar, MDTaking people
- University of Pittsburgh Medical CenterPittsburgh, United StatesContact: Gavin Hickey, MDTaking people
- Maine Medical CenterPortland, United StatesContact: Andrew Schwartzman, MDTaking people
- Providence St. Vincent Heart ClinicPortland, United StatesContact: Jacob Abraham, MDTaking people
- University of Washington Medical CenterSeattle, United StatesContact: Claudius Mahr, DOTaking people
- Cleveland Clinic FloridaWeston, United StatesContact: Jaime Hernandez-Montfort, MD MPHTaking people
About the trial
What the trial wants to find out
The Cardiogenic Shock Working Group is a multicenter registry where we collect de-identified clinical variables from the medical records and follow-up phone calls of shock patients from multiple institutions and centralize this data to a single registry for analysis of clinical outcomes.
The group in the trial
- Cardiogenic Shock Patients
Cardiogenic Shock patients eligible for this study are defined by at least one of the two categories below. 1. Patients have at least 2 of the following concurrently at any point during the index hospitalization: MAP \< 60mmHg or a \>30mmHg drop in MAP from baseline, SBP \< 90mmHg or a \>30mmHg drop in SBP from baseline, Pulse \> 100, Cardiac Index \< 2.2, Cardiac Power Output ≤ 0.6 or PAPI \< 1.0. 2. Patients require the use of at least 1 vasopressor, inotrope or acute mechanical circulatory support device to maintain values above the above targets.
Treatment: Vasopressor, Inotrope, and Acute Mechanical Circulatory Support Devices
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Cardiogenic Shock Working Group Registry
- Plain-language title
- Registry Tracking Outcomes in People With Cardiogenic ShockGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 27 October 2026