Tests 18F-DOPA PET imaging in people with several conditions
Studies how 18F-DOPA PET scans are performed in children and adults with various conditions.
Plain-language title generated from the registry record
Registry title: 18F-DOPA II - PET Imaging Optimization
Key facts
- Where
- Edmonton, CanadaSee the site
- Phase
- Phase 3
Where in Canada
- WC Mackenzie Health Science Centre / University of Alberta HospitalEdmonton, CanadaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Alberta
- Trial code
- NCT04706910
- Record updated
- 9 February 2026
- Original description
A single centre non-randomized, non-blinded phase III prospective cohort study of 18F-DOPA PET/CT imaging in specific patient populations:Read full original descriptionShow less
18F-DOPA II - PET Imaging Optimization
A single centre non-randomized, non-blinded phase III prospective cohort study of 18F-DOPA PET/CT imaging in specific patient populations:
1. Pediatric patients (less than 18 years old) with congenital hyperinsulinism. 2. Pediatric patients (less than 18 years old) with neuroblastoma. 3. Pediatric (less than 18 years old) or Adult patients (18 or older) with known or clinically suspected neuroendocrine tumor. 4. Adult patients (18 or older) with a clinical suspicion of Parkinson's disease or Lewy body dementia. 5. Pediatric (less than 18 years old) or Adult patients (18 or older) with brain tumors.
Image optimization (the primary study objective) and gallbladder activity pattern (the secondary objective) will be evaluated.
Inclusion: Pediatric patients (less than 18 years old) with congenital hyperinsulinism; Pediatric patients (less than 18 years old) with neuroblastoma; Pediatric (less than 18 years old) or Adult patients (18 or older) with known or clinically suspected neuroendocrine tumor; Adult patients (18 or older) with a clinical suspicion of Parkinson's disease or Lewy body dementia; Pediatric (less than 18 years old) or Adult patients (18 or older) with brain tumors.
Exclusion: History of previous cholecystectomy (excluded from dynamic abdomen sub-study only); Young pediatric patients (less than 13 years old) who are unable to lie flat for 20-30 minutes and for whom clinical sedation is contraindicated (as determined by a pediatric anaesthesiologist); Unable to obtain consent; Weight >225 kg (weight limitation of PET/CT scanner); Adult patients unable to lie flat for 20-30 minutes to complete the PET-CT session; Lack of intravenous access; Pregnancy.