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Tests a bedside brain-wave check using sounds in unconscious brain injury patients

Checks brain responses to music and speech in unconscious adults with brain injury.

Plain-language title generated from the registry record
Registry title: The EBC Recovery Study

Key facts

Where
Miami and New York, United StatesSee the 2 sites

Where in United States

  • Jackson Memorial HospitalMiami, United StatesTaking people
  • Columbia UniversityNew York, United StatesTaking people

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Trial details

Who runs it
University of Miami
Trial code
NCT04712591
Record updated
8 September 2026
Original description
The purpose of this research study to find out if clinically unconscious acute brain injury patients that show brain activation to music and language on electroencephalogram (EEG) (bedside test) have better outcomes and wake up in the future.Read full original descriptionShow less

Electrophysiologic Biomarkers of Consciousness (EBC) Recovery After Brain Injury

The purpose of this research study to find out if clinically unconscious acute brain injury patients that show brain activation to music and language on electroencephalogram (EEG) (bedside test) have better outcomes and wake up in the future.

Inclusion: For ABI Participants; ABI adult (18 years and older) patients who are admitted to the intensive care unit; Unconscious with Glasgow Coma Scale (GCS) \<8 on presentation and unable to follow bedside commands; A negative COVID-19 test on arrival; For Healthy Volunteers:; 18 years and older.

Exclusion: Patients with cardiac arrest on presentation; \<18 years of age; For All Participants:; Pregnant woman.

ClinicalTrials.gov NCT04712591