Enhancing Motor Learning in Children With Cerebral Palsy Using Transcranial Direct-current Stimulation
Reason given: Funding was not obtained so the study could not be conducted.
Trial details
- Who runs it
- Boston University Charles River Campus
- Trial code
- NCT04725019
- Record updated
- 13 August 2026
- Original description
The goal of this study is to test the effects of transcranial direct current stimulation (tDCS) on motor learning and brain plasticity in children with unilateral spastic cerebral palsy (USCP).Read full original descriptionShow less
The goal of this study is to test the effects of transcranial direct current stimulation (tDCS) on motor learning and brain plasticity in children with unilateral spastic cerebral palsy (USCP).
Inclusion: Children between 6-17 years old who have been diagnosed with cerebral palsy, with the following joint mobility: wrist extension 20º, metacarpophalangeal and proximal interphalangeal joints 10º. Ability to cooperate and follow simple directions.
Exclusion: Previous episode of unprovoked neurocardiogenic syncope; Orthopedic surgery in affected arm; Botulinum toxin therapy in either upper extremity during last 6 months, or planned during study period; Currently receiving intrathecal baclofen; History of broken arm (either arm) 1 year prior to study enrollment; Current use of medications known to lower the seizure threshold; Centrally-acting medications including anti-seizure medications; Evidence of scalp disease or skin abnormalities; Current medical illness unrelated to CP; Seizure beyond age 2, use of anti-seizure medication, history or family history of epilepsy, cranial metal implants, structural brain lesion, devices that may be affected by tDCS or TMS (pacemaker, medication pump, cochlear implant, implanted brain stimulator); True positive response on the Transcranial Magnetic Stimulation and MRI Safety Screen; Indwelling metal or incompatible medical devices; High motor ability in affected arm (i.e. no asymmetry in scores of hand function); Severe spasticity; Lack of asymmetry in hand function.