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Checks bone and muscle weakness in older adults having hip fracture surgery

Tests checkups for weak bones and muscles in adults 65 and older with hip fracture.

Plain-language title generated from the registry record
Registry title: Study of Parameters of Osteosarcopenia in Patients With Hip Fracture

Key facts

Where
Bologna, ItalySee the site

Where in Italy

  • Istituto Ortopedico RizzoliBologna, ItalyTaking people

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Trial details

Who runs it
Istituto Ortopedico Rizzoli
Trial code
NCT04730622
Record updated
22 May 2026
Original description
The study aims to assess the adequacy of a set of clinical and laboratory investigations for identifying the osteosarcopenia status in patients undergoing a hip replacement for a fragility fracture of the femoral neck. The control group will consist of patients undergoing a hip replacement for osteoarthritis, as the decrease in muscle function and bone quality is less severe in this condition than in osteoporosis.Read full original descriptionShow less

Study of Parameters of Bone Fragility and Sarcopenia in Patients Undergoing Surgery for Fracture of the Femoral Neck

The study aims to assess the adequacy of a set of clinical and laboratory investigations for identifying the osteosarcopenia status in patients undergoing a hip replacement for a fragility fracture of the femoral neck. The control group will consist of patients undergoing a hip replacement for osteoarthritis, as the decrease in muscle function and bone quality is less severe in this condition than in osteoporosis.

Inclusion: Patients who came to observation with femoral neck fracture of possible osteoporotic nature (no or minimal trauma) to be treated with endoprosthesis or hip arthroplasty; Competent patients who have signed consent to participate in the study (see Informed Consent section of this protocol).

Exclusion: Previous osteoporotic fractures; Previous prosthetic surgery for orthopedic diseases; Chronic treatment with anti-osteoporotic drugs, immunosuppressive drugs, and insulin; Pre-existing clinical conditions that led to permanent immobility; Neoplastic diseases; Autoimmune diseases; Chronic viral infections (HBV, HCV, HIV); Paget's disease; Severe myopathies.

ClinicalTrials.gov NCT04730622