Follows children and young adults treated with radiotherapy for cancer
Observes long-term health and social effects of modern radiotherapy in young cancer patients.
Plain-language title generated from the registry record
Registry title: Health Effects of CArdiac FluoRoscopy and MOderN RadIotherapy in PediatriCs - Radiotherapy
Key facts
- Where
- Leuven, BelgiumSee the site
Where in Belgium
- KU LeuvenLeuven, BelgiumTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Institut National de la Santé Et de la Recherche Médicale, France
- Trial code
- NCT04746729
- Record updated
- 3 August 2026
- Original description
The goal of the HARMONIC-RT study is to evaluate late health and social outcomes of contemporary techniques of external beam radiotherapy in paediatric patients, based on the setting-up of a European, long-term registry complemented by a biobank.Read full original descriptionShow less
Health Effects of CArdiac FluoRoscopy and MOderN RadIotherapy in PediatriCs - Radiotherapy (HARMONIC-RT)
The goal of the HARMONIC-RT study is to evaluate late health and social outcomes of contemporary techniques of external beam radiotherapy in paediatric patients, based on the setting-up of a European, long-term registry complemented by a biobank.
Inclusion: First external beam radiation therapy (EBRT) started in 2000 or after for management of a first primary neoplasm; Age under 22 years at the time of first EBRT initiation; Radiation treatment plan (first EBRT) stored in DICOM format; Usual residency in the country of EBRT to enable a long-term follow-up; Scheduled first EBRT for management of a first primary neoplasm; Age under 22 years at the time of scheduled first EBRT; Radiation treatment plan stored in DICOM format; Affiliate or beneficiary of health insurance (or any required equivalent as defined in applicable national law); Usual residency in the country of EBRT to enable a long-term follow-up; Signed informed consent/assent.
Exclusion: Prior external or internal radiation therapy; Prior external or internal radiation therapy; Patients with poor prognosis (e.g. diffuse pontine glioma or high grade glioma) at first EBRT initiation; Patients who refused to participate in the study; Prospective inclusion of study participants; Patients with poor prognosis (e.g. diffuse pontine glioma or high grade glioma); Protected adults (persons under curatorship, tutorship / individuals under guardianship by court order, persons deprived of their liberty); Adult/parent(s)/legal representative(s) who cannot read or understand the informed consent in the applicable language(s) in the country of EBRT.
Retrospective inclusion of study participants.