Not yet taking people in United StatesNo phase

Remote Monitoring of Falls and Movement in Progressive Supranuclear Palsy

Uses wearable sensors to track falls, movement, speech and thinking in adults with PSP.

Key facts

Who runs it: Massachusetts General Hospital
Where: Baltimore and Boston, United StatesSee the 2 sites
Trial code: NCT04753320
Registry title: Remote Monitoring in Progressive Supranuclear Palsy (PSP)
Status: Not yet recruiting
People taking part: 85 people, planned
Started: 1 Sept 2026
Expected to end: Dec 2028
Type of study: Observational
Record updated: 29 July 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with progressive supranuclear palsy (PSP), Parkinson's disease or multiple system atrophy, and for healthy controls. It measures falls, movement, speech and thinking with wearable sensors.

Age: 18 to 89 years
Sex: All sexes can join.
Disease stage: Possible or probable PSP, at least probable Parkinson's disease, or at least probable multiple system atrophy, as defined by MDS criteria. Healthy controls can also join.

Main reasons for not taking part

Another neurological, medical or psychiatric condition that stops the person taking part, in the investigator's judgment
More than 5 falls a month
Needing a walker to walk safely
Cannot walk 10 feet without help
No caregiver able to help with the study tasks

The registry criteria, word for word

Show all 9 criteriaShow less

Who can take part

Clinical diagnosis of possible or probable PSP phenotype as defined by the 2017 MDS criteria, clinical diagnosis of at least probable PD as defined by the 2015 MDS criteria, or clinical diagnosis of at least probable MSA as defined by the 2022 MDS criteria, or healthy controls
Male or female, aged 18 to 89 years, inclusive
Fluent in reading and speaking English
Capable of providing informed consent based on the investigator's judgment
Able to comply with the protocol based on the investigator's judgment
Able to walk 10 feet unassisted
With access to a caregiver who is able to assist with all study-related procedures

Who cannot take part

Any neurological, medical, or psychiatric condition that would preclude participation in study activities based on the investigator's judgment
A history of frequent falls defined as more than 5 falls/month or requirement of a walker to ambulate safely

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

Are you between 18 and 89 years old?

Where in United States

Johns HopkinsBaltimore, United StatesContact: AJ HallNot yet recruiting
Massachusetts General HospitalBoston, United StatesContact: Yvonne Kim, BSNot yet recruiting

About the trial

What the trial wants to find out

This is a single-arm, longitudinal, observational study on the use of wearable sensors and digital health technology to measure fall frequency and motor, speech, and cognitive function in patients with PSP over the course of approximately one year. Participants will perform supervised remote assessments monthly and in-person assessments approximately every 6 months.