Studies heart rhythm treatment after cardiac surgery in atrial fibrillation patients
Observes low-energy cardioversion and pacing in adults with atrial fibrillation after heart surgery.
Plain-language title generated from the registry record
Registry title: The DefiPace Study
Key facts
- Where
- Vienna, AustriaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults who are scheduled for planned open-chest heart surgery (bypass and/or valve surgery) and have never had atrial fibrillation.
- Age
- At least 18 years old. People having bypass surgery alone must be at least 70 years old. People having valve surgery must be at least 60 years old.
- Sex
- All sexes can join.
- Disease stage
- Planned (elective) open-chest heart surgery: bypass and/or valve surgery. No past history of atrial fibrillation.
Main reasons for not taking part
- Past history of permanent, persistent or paroxysmal atrial fibrillation
- Permanent pacemaker or defibrillator, or other active electronic device implanted in the heart
- Minimally invasive surgery
- Stroke within the last 3 months
- Past or current endocarditis (infection of the heart lining)
Read by machine on 12 November 2026.
Where in Austria
- Medical University of ViennaVienna, AustriaContact: Emilio Osorio, Dr. med.Taking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Institut für Pharmakologie und Präventive Medizin
- Trial code
- NCT04804748
- Record updated
- 30 July 2026
- Original description
Prospective, non-interventional, multi-center, international registry in two phases in consecutive patients undergoing elective cardiac surgery.Read full original descriptionShow less
Safety and Efficacy of Low-energy Electrical Cardioversion With or Without Bi-atrial Pacing in Patients With Post-operative Atrial Fibrillation in a Real World Setting - The DefiPace Study
Prospective, non-interventional, multi-center, international registry in two phases in consecutive patients undergoing elective cardiac surgery.
The DefiPace registry is designed in two phases
1. to document the standard of care in 50 patients with atrial fibrillation (AF) 2. to assess the treatment and outcomes of patients with post-operative atrial fibrilllation using low-energy cardioversion and subsequent bi-atrial pacing in clinical practice in 100 patients
Inclusion: Patient is scheduled to undergo elective open chest cardiac surgery (bypass and / or valve surgery); Patient is at least 18 years old; Patient with isolated bypass surgery is at least 70 years old; Patient with valve surgery is at least 60 years old; Patient provides written informed consent prior to the procedure; Phase B only: patient is scheduled for TMA implantation during the elective cardiac surgery and is potentially eligible for DefiPace use.
Exclusion: Minimally-invasive surgery; Pregnacy at the time of surgery; Clinical history of either permanent, persistend or paroxysmal atrial fibrillation; Permanent pacemaker/defibrillator, other intra-cardiac active implanted electronic devices; Recent stroke within the last 3 months; A history of or current endocarditis.