NCT04806620Recruiting
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
Unhide® Project Also Known as The Unhide® Solve Together Unified Platform
Source: ClinicalTrials.gov · Last updated 22 Jan 2026
Brief summary (registry, in English)
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related neuroinflammatory conditions. Participants in the United States aged 2 years and older will provide self-reported health data, biometrics, and symptom diaries through the MyDataHelps™ app (branded as unhide® for this study). The goal is to create comprehensive longitudinal profiles to facilitate research into disease subtypes, causes, diagnostics, and potential treatments, as well as to identify potential participants for future optional studies. "Healthy" individuals without brain inflammation are also eligible to participate. The digital health research platform used in this study was originally developed and designed by Solve M.E and was called SolveTogether. The Brain Inflammation Collaborative (BIC) expanded upon Solve M.E.'s work to include related diagnoses, pediatric participants, enhance symptom tracking, and more. BIC and Solve M.E. combined Solve Together and unhide®, to create The unhide® Solve Together Unified Platform in 2025.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 10000 (estimated)
- First submitted
- 17 Mar 2021
- Start date
- 5 Jul 2023
- Primary completion date
- 30 Jun 2030
- Lead sponsor
- Brain Inflammation Collaborative
- Diseases
- Migraine, Myasthenia gravis, Bipolar disorder, Long COVID and ME/CFS, Multiple sclerosis, Crohn's disease, Ulcerative colitis, Rheumatoid arthritis, Psoriasis, Psoriatic arthritis, Ankylosing spondylitis, Endometriosis
- NCT number
- NCT04806620
What you commit to
- Study type: Observational
- Planned participants: 10000
- From 5 Jul 2023 to the primary completion date, 30 Jun 2030
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Criteria the registry did not label
- Participants may be either self-diagnosed, or diagnosed by a physician with the following conditions:
- Infection-associated chronic conditions such as Long COVID, chronic Lyme, myalgic encephalomyelitis (ME/CFS), and post-acute neuropsychiatric syndrome (PANS/PANDAS).
- Neuroimmune, developmental, autonomic, and neurological conditions like migraines, dysautonomia, POTS, multiple sclerosis, and autism spectrum disorder.
- Autoimmune diseases such as Lupus, Sjogren's Disease, rheumatoid arthritis, myasthenia gravis, ankylosing spondylitis, and related autoimmune conditions.
- Inflammatory gastrointestinal conditions such as Crohn's Disease, Celiac Disease, and ulcerative colitis.
- Behavioral and mood disorders such as anxiety, depression, bipolar disorder, PTSD, eating disorders, OCD, and other related conditions.
- "Healthy" people (without brain inflammation), including unaffected individuals, unaffected individuals in the same household, and unaffected individuals who are married to relatives and family members.
- Have consistent internet access and a cell phone, tablet, or PC since this is an online or app-based platform that requires entering data and completing surveys.
- Currently live in the United States
- Be able to participate in English (stay tuned for updates about the Spanish language version)
- Be willing to share symptom and health data through the platform
Age in the registry: 2 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Brain Inflammation Collaborative Coordinator of this site? Confirm its status | Delafield | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.