New MRI Scan Method for Spinal Cord Lesions in Multiple Sclerosis
Tests a new spinal cord MRI scan to find multiple sclerosis lesions in adults.
Plain-language title generated from the registry record
Registry title: Spinal Cord Lesion Detection in Multiple Sclerosis Using Novel MRI Sequences
Key facts
- Where
- Basel, SwitzerlandSee the site
Where in Switzerland
- University Hospital Basel, Department of NeurologyBasel, SwitzerlandTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital, Basel, Switzerland
- Trial code
- NCT04819737
- Record updated
- 5 March 2026
- Original description
This study is to evaluate the sensitivity and intra-/inter-observer agreement of the averaged magnetization inversion recovery acquisitions (AMIRA) in spinal cord (SC) Multiple sclerosis (MS) lesion detection and to evaluate the additional clinical value of this sequence in clinical settings.Read full original descriptionShow less
Spinal Cord Lesion Detection in Multiple Sclerosis Using Novel MRI Sequences: A Pilot Study
This study is to evaluate the sensitivity and intra-/inter-observer agreement of the averaged magnetization inversion recovery acquisitions (AMIRA) in spinal cord (SC) Multiple sclerosis (MS) lesion detection and to evaluate the additional clinical value of this sequence in clinical settings.
Inclusion: Diagnosis of multiple sclerosis according to established international criteria; Steroid free period: > 4 weeks; Participation in the Swiss MS Cohort (SMSC) study.
Exclusion: . History of severe (other) neurological, internal or psychiatric disease with SC affection; MRI-related exclusion criteria (questionnaire):; Paramagnetic and/or superparamagnetic foreign objects in the body (especially when located close to the SC); Pacemaker; Claustrophobia; Pregnancy, lactation; Known hypersensitivity to gadolinium-based contrast media.