Studies how often atopic dermatitis affects the eyelids in adults
Observes how often eyelid skin is affected in adults with atopic dermatitis.
Plain-language title generated from the registry record
Registry title: Frequency of Palpebral Involvement in Adult With Atopic Dermatitis
Key facts
- Where
- Lille and Rouen, FranceSee the 2 sites
Where in France
- Hop Claude Huriez Chu LilleLille, FranceTaking people
- Hopital Charles Nicolle Chu RouenRouen, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital, Lille
- Trial code
- NCT04826744
- Record updated
- 23 December 2025
- Original description
Atopic dermatitis is a common inflammatory skin disease, resulting from genetical, immunological and environmental factors. Head and neck are among the most frequent involved areas, almost 50% in adult patients according to most publications. Palpebral involvement is also common and a source of major quality of life impairment for patients.Read full original descriptionShow less
Frequency of Palpebral Involvement in Adult Atopic Dermatitis, in a Cohort of Patients From Lille and Rouen (France) ; a Multicenter Prospective Study
Atopic dermatitis is a common inflammatory skin disease, resulting from genetical, immunological and environmental factors. Head and neck are among the most frequent involved areas, almost 50% in adult patients according to most publications. Palpebral involvement is also common and a source of major quality of life impairment for patients.
However, the real frequency of this palpebral involvement is unknown, only estimated about 20% in few studies. The treatment of this location remains difficult, regarding to the thickness of palpebral skin and proximity of the eye.
To our knowledge, no prospective studies about allergological skin tests (such as patch-tests) in atopic patients with palpebral involvement had been conducted.
Finally, atopic dermatitis is frequently associated with ophthalmological diseases such as conjunctivitis, keratoconus or cataract, which belong to the minor criteria of Hanifin and Rakja classification.
A better knowledge of the atopic dermatitis palpebral involvement and the associated factors seems to be needed to improve the treatment and the quality of life of patients
Inclusion: Atopic Dermatitis according to the revised Hanifin and Rakja criteria (UK Working Party); Oral consent; Valid social insurance.
Exclusion: Personal history of uncontrolled asthma; Age under 18; No social insurance; Protective measures; Pregnancy or breast-feeding.