Evaluation of the Autonomic Nervous System in Patients Undergoing Esophagectomy for Cancer
Key facts
- Who runs it
- Centre Hospitalier Universitaire de Saint Etienne
- Where
- France1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Withdrawn
- Started
- Dec 2023
- Ended
- Sept 2024
- Type of study
- Observational
- Treatments tested
- Holter ECG
- Questionary
- Pupillometry
- Record updated
- 24 November 2023
- Why it stopped
- Due to a lack of staff in the department, no inclusion could be realized.
Who can take part
- Age
- 18 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 6 criteriaShow less
Who can take part
- Esophagectomy for cancer
- written and oral agreement
Who cannot take part
- pregnant women,
- patients with permanent atrial fibrillation,
- patients with pace-maker
- Patients under guardianship/curatorship
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
Esophageal surgery is a complex surgery, with high post-operative morbidity and mortality. The incidence of complications associated with esophagectomy varies from 17% to 74%, in the literature. A section of vagus nerves is conventionally performed during esophagectomy for cancer, because of oncological margins. The vagus nerve is responsible for the parasympathetic innervation at the gastrointestinal level, but also at the cardiac and pulmonary level. The post-operative morbidity of these procedures could be linked in part to the bilateral section of the vagus nerves, because of their impact on the autonomous regulation of this vital functions. The main objective of the study is to find a modification of the sympathomimetic balance pre and post operatively, in patients undergoing esophagectomy.
Treatments tested
- Holter ECG
- Questionary
- Pupillometry
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Prospective Monocentric Evaluation of the Autonomic Nervous System in Patients Undergoing Esophagectomy for Cancer
- Record updated
- 24 November 2023