Catheter Ablation of Ventricular Arrhythmia Reduces Skin Sympathetic Activity
Reason given: This study was closed before its planned primary completion date because early data indicated that VT ablation had little impact on sympathetic nerve activity in short-term follow up.
Key facts
- Where
- Rochester, United StatesSee the site
Where in United States
- Mayo Clinic in RochesterRochester, United StatesNo longer taking part
Trial details
- Who runs it
- Mayo Clinic
- Trial code
- NCT04837183
- Record updated
- 3 July 2024
- Original description
This study is being done to determine whether there is an increase in sympathetic nerve activity before the onset of ventricular arrhythmias or irregular heartbeat rhythm. In addition, this study is looking at the relationship between sympathetic nerve activity and how patients with ventricular arrhythmias respond to catheter ablation treatment.Read full original descriptionShow less
This study is being done to determine whether there is an increase in sympathetic nerve activity before the onset of ventricular arrhythmias or irregular heartbeat rhythm. In addition, this study is looking at the relationship between sympathetic nerve activity and how patients with ventricular arrhythmias respond to catheter ablation treatment.
Inclusion: Patients who have non-sustained or sustained VA (VA ≥ 30s or receiving appropriate ICD therapies) are presented to the clinic or admitted to the hospital within 7 days of episodes; The causes of VA are associated with structural heart diseases including ischemic or nonischemic cardiomyopathy (idiopathic cardiomyopathy, hypertrophic cardiomyopathy, cardiac sarcoidosis or amyloidosis, and arrhythmogentic right ventricular dysplasia); Subjects are 18 years of age and older.
Exclusion: Allergic to skin patch electrodes; Female patients who is pregnant or of childbearing potential and not on a reliable form of birth control; Vulnerable populations (fetuses, neonates, pregnant women, prisoners, institutionalized individuals).