Studies which factors predict recovery after stroke from large-artery narrowing
Observes hospital patients with ischemic stroke from artery blockage to find outcome predictors.
Plain-language title generated from the registry record
Registry title: Study of Predictive Factors Related to Prognosis of Patients With Ischemic Stroke Due to Large-artery Atherosclerosis
Key facts
- Where
- Wuhan, ChinaSee the site
Where in China
- Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyWuhan, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Tongji Hospital
- Trial code
- NCT04847752
- Record updated
- 20 June 2024
- Original description
This is a single-center prospective cohort study of predictive factors related to prognosis of ischemic stroke due to large-artery atherosclerosis.Read full original descriptionShow less
A Prospective Observational Cohort Study of Predictive Factors Related to Prognosis of In-hosiptal Patients With Ischemic Stroke Due to Large-artery Atherosclerosis
This is a single-center prospective cohort study of predictive factors related to prognosis of ischemic stroke due to large-artery atherosclerosis.
From March 1, 2021 to December 31, 2026, 1000 patients with ischemic stroke due to large-artery atherosclerosis who are admitted to the Department of Neurology or Neurosurgery, Tongji Hospital are going to be recruited. Detailed clinical data in emergency room and in-hospital will be obtained from the medical record reviews, and the National Institutes of Health Stroke Scale (NIHSS) and Modified Rankin Scale (mRS) score will be done by certified neurologists to assess the severity of the disease in acute stage and treatment outcome during the follow-up. All cases will undergo routine blood tests, brain magnetic resonance imaging (MRI) and cerebral vascular examination, such as TCD, CTA, HRMR or DSA. The investigators will analyze the in-hospital factors that could predict the outcome to provide more evidence-based suggestions in the treatment and prognosis of atherosclerotic ischemic cerebrovascular disease.
Inclusion: Ischemic stroke due to large-artery atherosclerosis has been proved by clinical symptoms and imaging examinations; Symptomatic superior arch stenosis >50%; Asymptomatic superior arch stenosis was >70%; written informed consent was obtained from patients or their surrogates before enrollment.
Exclusion: Brain CT or MRI showing cerebral hemorrhage (excluded ischemic stroke with hemorrhage transformation); With severe systemic disease, are expected to survive < 3 months; Patients will not able to provide continuous follow-up information.