Studying Stroke Patients With Extensive Early Brain Damage Who Receive Clot Removal
Observes adults with acute ischemic stroke who receive endovascular treatment, testing brain scan measures.
Plain-language title generated from the registry record
Registry title: Improving Low ASPECTS Stroke Thrombectomy
Key facts
- Where
- Berlin, Bremen, Hamburg, Kaiserslautern, Marburg, Münster, and Rostock, GermanySee the 7 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with an acute stroke caused by a blocked brain artery, who have a low early CT score (ASPECTS 0-5) and are treated by removing the clot through a catheter. Care stays routine; data are only collected.
- Age
- Older than 18 years
- Sex
- All
- Disease stage
- Acute ischemic stroke, with ASPECTS of 0-5 and a confirmed lasting blockage of the terminal carotid artery, a middle cerebral artery (M1 or M2) or the basilar artery that fits the symptoms.
Read by machine on 9 November 2026.
Where in Germany
- Charite University, BerlinBerlin, GermanyEnrolling by invitation
- Hospital Bremen-MitteBremen, GermanyEnrolling by invitation
- University Medical Center Hamburg-EppendorfHamburg, GermanyTaking people
- WestpfalzklinikumKaiserslautern, GermanyEnrolling by invitation
- University Hospital MarburgMarburg, GermanyTaking people
- University MünsterMünster, GermanyEnrolling by invitation
- University RostockRostock, GermanyEnrolling by invitation
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Universitätsklinikum Hamburg-Eppendorf
- Trial code
- NCT04862507
- Record updated
- 24 May 2023
- Original description
Improving Low ASPECTS Stroke Thromectomy (I-LAST) is an academic, independent, prospective, multicenter, observational registry study. Consecutive patients treated with endovascular stroke treatment will be enrolled in German stroke centers. Patients receive regular care and data will be collected as part of clinical routine. Baseline clinical and procedural information as well clinical follow-up information during in-hospital stay, and up to 90 days of stroke onset are collected. Data collected include demographics, National Institute of Health Stroke Scale (NIHSS) on admission, pre-treatment ASPECTS, information on timing and success of interventional treatment, procedural complications, intracranial hemorrhage, and functional outcome. Advanced imaging biomarkers will be tested and validated aiming to improve treatment selection and outcome prediction of patients presenting with extensive baseline infarction.Read full original descriptionShow less
Improving Low Alberta Stroke Program Early ct Score Stroke Thrombectomy
Improving Low ASPECTS Stroke Thromectomy (I-LAST) is an academic, independent, prospective, multicenter, observational registry study. Consecutive patients treated with endovascular stroke treatment will be enrolled in German stroke centers. Patients receive regular care and data will be collected as part of clinical routine. Baseline clinical and procedural information as well clinical follow-up information during in-hospital stay, and up to 90 days of stroke onset are collected. Data collected include demographics, National Institute of Health Stroke Scale (NIHSS) on admission, pre-treatment ASPECTS, information on timing and success of interventional treatment, procedural complications, intracranial hemorrhage, and functional outcome. Advanced imaging biomarkers will be tested and validated aiming to improve treatment selection and outcome prediction of patients presenting with extensive baseline infarction.
Inclusion: Clinical diagnosis of acute ischemic stroke; ASPECTS of 0-5; Confirmed diagnosis of persistent occlusion of terminal carotid artery, middle cerebral artery (M1 or M2), or basilar artery consistent with symptoms; Age >18 years; Ethic approval in process.
Exclusion: none.