Zenith® Fenestrated+ Clinical Study
Key facts
- Where
- Ann Arbor, Atlanta, Baltimore, Birmingham, Boston, Chapel Hill, Charleston, Chicago, Cleveland, Dallas, Gainesville, Glenview, Houston, Indianapolis, Kingsport, La Jolla, Lebanon, Los Angeles, Maywood, Naperville, New York, Philadelphia, Pittsburgh, Roanoke, Rochester, St Louis, Stanford, Tampa, Washington D.C., and Worcester, United StatesSee the 32 sites
Where in United States
- University of Michigan Health SystemAnn Arbor, United StatesContact: Jonathan Eliason, MDTaking people
- Emory University HospitalAtlanta, United StatesContact: Yazan Duwayri, MDTaking people
- University of MarylandBaltimore, United StatesContact: Shahab Toursavadkohi, MDTaking people
- University of Alabama Birmingham HospitalBirmingham, United StatesContact: Adam Beck, MDTaking people
- Beth Israel Deaconess Medical CenterBoston, United StatesContact: Marc Schermerhorn, MDTaking people
- Massachusetts General HospitalBoston, United StatesContact: Chanda Bell, RN, BSNNo longer taking part
- University of North Carolina at Chapel HillChapel Hill, United StatesContact: Federico Parodi, MDTaking people
- Medical University of South CarolinaCharleston, United StatesContact: Ravi Veeraswamy, MDTaking people
- Northwestern Memorial HospitalChicago, United StatesContact: Neel Mansukhani, MDTaking people
- Cleveland Clinic FoundationCleveland, United StatesContact: Francis Caputo, MDTaking people
- UT SouthwesternDallas, United StatesContact: Mirza Baig, MDTaking people
- University of Florida Shands HospitalGainesville, United StatesContact: Zain Shahid, MDTaking people
- Endeavor Health Cardiovascular Institute at Glenbrook HospitalGlenview, United StatesContact: George PontikisTaking people
- Memorial Hermann Texas Medical Center UT HealthHouston, United StatesContact: Naveed Saqib, MDTaking people
- Methodist Hospital of IndianaIndianapolis, United StatesContact: Andres Fajardo, MDTaking people
- Holston Valley HospitalKingsport, United StatesContact: Robert "Bo" Allen, MDTaking people
- UC San DiegoLa Jolla, United StatesContact: Mahmoud Malas, MDTaking people
- Dartmouth Hitchcock Medical CenterLebanon, United StatesContact: Bjoern Suckow, MDTaking people
- University of Southern CaliforniaLos Angeles, United StatesContact: Sukgu Han, MDTaking people
- Loyola University Medical CenterMaywood, United StatesContact: Michael Soult, MDTaking people
- Edward HospitalNaperville, United StatesContact: George Pontikis, MDTaking people
- Columbia University Irving Medical Center/NY Presbyterian HospitalNew York, United StatesContact: Virenda PatelTaking people
- New York University Langone Medical CenterNew York, United StatesContact: Thomas Maldonado, MDTaking people
- Hospital of the University of PennsylvaniaPhiladelphia, United StatesContact: Grace Wang, MDTaking people
- University of Pittsburgh Medical CenterPittsburgh, United StatesContact: Nathan LiangTaking people
- Carilion Roanoke Memorial HospitalRoanoke, United StatesContact: Chanda Bell, RN, BSNNo longer taking part
- Mayo ClinicRochester, United StatesContact: Randall DeMartino, MDTaking people
- Barnes-Jewish HospitalSt Louis, United StatesContact: John Ohman, MDTaking people
- Stanford Hospitals and ClinicsStanford, United StatesContact: Jason Lee, MDTaking people
- Tampa General HospitalTampa, United StatesContact: Dean Arnaoutakis, MDTaking people
- MedStar Washington Hospital CenterWashington D.C., United StatesContact: Steven Abramowitz, MDTaking people
- University of MassachusettsWorcester, United StatesContact: Andres Schanzer, MDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Cook Research Incorporated
- Trial code
- NCT04875429
- Record updated
- 6 October 2026
- Original description
The Zenith® Fenestrated+ Endovascular Graft Clinical Study will assess the safety and effectiveness of the Zenith® Fenestrated+ Endovascular Graft (ZFEN+) in combination with the BeGraft Balloon-Expandable FEVAR Bridging Stent Graft System (BeGraft) and Unibody2 for the treatment of patients with aortic aneurysms involving one or more of the major visceral arteries.Read full original descriptionShow less
Zenith® Fenestrated+ Endovascular Graft Clinical Study
The Zenith® Fenestrated+ Endovascular Graft Clinical Study will assess the safety and effectiveness of the Zenith® Fenestrated+ Endovascular Graft (ZFEN+) in combination with the BeGraft Balloon-Expandable FEVAR Bridging Stent Graft System (BeGraft) and Unibody2 for the treatment of patients with aortic aneurysms involving one or more of the major visceral arteries.
Up to 130 additional subjects may be enrolled in Continued Access phase of the study
Exclusion: Simultaneous participation in another investigation study, unless the patient is at least 30 days beyond the primary endpoint of any previous study; Age < 18 years; Life expectancy < 2 years; Pregnant, breast-feeding, or planning to become pregnant within 60 months; Inability or refusal to give informed consent by the patient or legally authorized representative; Unwilling or unable to comply with the follow-up schedule, required clinical assessments, and imaging.
Include Criteria:; Thoracoabdominal, pararenal or juxtarenal aortic aneurysm with a diameter ≥ 55 mm for males and ≥ 50 mm for females; Thoracoabdominal, pararenal or juxtarenal aortic aneurysm with a growth rate of ≥ 5 mm in 6 months; Thoracoabdominal, pararenal or juxtarenal aortic aneurysm with aortic diameter > 2x the normal aortic diameter or saccular aneurysm that warrants treatment in the opinion of the investigator.