Brain-Activity Training With Imagery for Reading Problems After Stroke
Tests brain-activity training with hand imagery in adults with reading problems after stroke.
Plain-language title generated from the registry record
Registry title: Neurofeedback Intervention for Reading Deficits in Subacute Stroke
Key facts
- Where
- West Orange, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT04875936, who can take part
Where in United States
- Kessler FoundationWest Orange, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Kessler Foundation
- Trial code
- NCT04875936
- Record updated
- 8 May 2026
- Original description
The overall goal of this project is to advance a biologically-based approach to treatment of reading disorders after stroke, which will expand the limits of cognitive rehabilitation. Using a novel brain imaging technique, called real-time functional magnetic resonance imaging (fMRI) neurofeedback combined with right hand motor imagery, this project will re-instate brain activity in the left language-dominant hemisphere. Stroke patients will practice modulating their own brain activity using fMRI neurofeedback signal and will select the most effective mental strategies that help them maintain brain activation patterns associated with better reading recovery.Read full original descriptionShow less
Rehabilitation of Reading Deficits in Subacute Stroke Using Functional Magnetic Resonance Imaging (fMRI) Neurofeedback and Motor Imagery
The overall goal of this project is to advance a biologically-based approach to treatment of reading disorders after stroke, which will expand the limits of cognitive rehabilitation. Using a novel brain imaging technique, called real-time functional magnetic resonance imaging (fMRI) neurofeedback combined with right hand motor imagery, this project will re-instate brain activity in the left language-dominant hemisphere. Stroke patients will practice modulating their own brain activity using fMRI neurofeedback signal and will select the most effective mental strategies that help them maintain brain activation patterns associated with better reading recovery.
Inclusion: First-ever left-hemisphere stroke < 3 months prior to study recruitment or healthy volunteer; Age: 18 - 80 years old; Fluent and literate in English prior to stroke; Reading deficits, defined as >3 errors on the Paragraphs test (subtests VIII, IX) of the Reading Comprehension Battery for Aphasia-2nd ed. (RCBA-2) in keeping with the healthy control accuracy criterion of 86-100% correct.
Exclusion: Inability to undergo MRI (e.g., pregnancy, non-MRI compatible implants, claustrophobia); A history of prior neurological disease (e.g., brain tumor, Alzheimer's disease); Inability to consent or complete study tasks.