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Compression Garments in the Community With POTS

This trial has no sites in United States.

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Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 60 years old?

Source: NCT04881318, who can take part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

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Trial details

Who runs it
University of Calgary
Trial code
NCT04881318
Record updated
7 May 2026
Original description
Compression Garments are a commonly prescribed treatment in Postural Orthostatic Tachycardia Syndrome (POTS). The effectiveness of a proof-of-concept compression garment has been demonstrated in an acute laboratory setting. It is not known if commercially available compression garments that participants wear in their every day lives are effective at improving heart rate and reducing symptoms in POTS. This trial will evaluate the use of commercially available waist-high and abdominal compression garments in adults diagnosed with POTS in a community setting.Read full original descriptionShow less

Compression Garments are a commonly prescribed treatment in Postural Orthostatic Tachycardia Syndrome (POTS). The effectiveness of a proof-of-concept compression garment has been demonstrated in an acute laboratory setting. It is not known if commercially available compression garments that participants wear in their every day lives are effective at improving heart rate and reducing symptoms in POTS. This trial will evaluate the use of commercially available waist-high and abdominal compression garments in adults diagnosed with POTS in a community setting.

Inclusion: Physician diagnosis of Postural Tachycardia Syndrome (POTS); Resident of Canada; Owns waist-high compression garment: medical grade or commercially available tights with a pressure rating provided (e.g. 15-18 mmHg, 20-30 mmHg, 30-40 mmHg); Optional Sub-Study: owns an abdominal compression garment (e.g. abdominal shapewear, waist high shorts); Able to participate in a 4-day study (2x2 day segments with a 5-day washout period).

Exclusion: Other factors which in the investigator's opinion would prevent the participant from completing the protocol, including poor compliance during previous studies; Overt cause for postural tachycardia (i.e., acute dehydration, thyroid disease) that precludes POTS diagnosis; Not a resident of Canada; Participants with somatization or severe anxiety symptoms will be excluded; Pregnant (self-reported); Inability to tolerate compression garments for the duration of the study; Does not own a waist-high compression garment.

ClinicalTrials.gov NCT04881318