Brain stimulation with cognitive therapy for thinking problems after stroke
Tests mild brain stimulation with thinking exercises in adults recovering from stroke.
Plain-language title generated from the registry record
Registry title: Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke
Key facts
- Where
- Philadelphia, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 90 years old?
Source: NCT04897334, who can take part
Where in United States
- Penn Medicine RehabilitationPhiladelphia, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Pennsylvania
- Trial code
- NCT04897334
- Record updated
- 9 January 2026
- Original description
The purpose of this study is to determine whether a non-invasive brain stimulation technique, transcranial direct current stimulation (tDCS), combined with traditional cognitive therapy will improve cognitive function in patients with subacute stroke.Read full original descriptionShow less
Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke (TRAINS): Neuromodulatory Intervention to Ameliorate Cognition After Stroke for Individuals At Risk for VCID.
The purpose of this study is to determine whether a non-invasive brain stimulation technique, transcranial direct current stimulation (tDCS), combined with traditional cognitive therapy will improve cognitive function in patients with subacute stroke.
Inclusion: Stroke that occurred within 4 weeks of the study; Presence of cognitive impairment attributable to stroke; Between the ages of 18 and 90; Able to understand the nature of the study and give informed consent; Able to follow simple commands as evidenced by NIHSS subtest 1C =0.
Exclusion: Current abuse of alcohol or drugs (prescription or otherwise); Metallic objects in the face or head other than dental apparatus such as braces, fillings, and implants; History of chronic, serious, or unstable neurologic illness other than stroke; Current unstable medical illness(es); History of reoccurring seizures or epilepsy; Active and severe psychiatric disorder; Pregnancy.