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Tests a new MRI scan for spinal cord lesions in multiple sclerosis

Tests a new MRI scan to detect spinal cord injury in adults with multiple sclerosis.

Key facts

Who runs it
Fondation Ophtalmologique Adolphe de Rothschild
Where
Paris, FranceSee the site
Trial code
Registry title
Evaluation of New MRI Sequences Including 3D-FGAPSIR for the Optimization of Inflammatory Spinal Cord Lesions Research
Status
Recruiting
People taking part
200 people, planned
Started
25 Oct 2023
Planned end
Oct 2026
Type of study
Observational
Treatments tested
  • MRI
Record updated
5 January 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults who already have a planned 3T MRI of the spinal cord to check for inflammation of the nervous system. An extra 10-minute MRI sequence is added.

Age
Over 18 years old
Sex
All sexes can join
Disease stage
People having a first check or a re-check of inflammation affecting the nervous system (nevrax).

Main reasons for not taking part

  • Being under a legal protection measure
  • Being pregnant, in labour or breastfeeding
  • Any absolute or relative reason not to have an MRI

The registry criteria, word for word

Show all 7 criteriaShow less

Who can take part

  • Patient over 18 years old
  • To benefit from a medullary exploration planned by 3T MRI as part of a first evaluation or a reassessment of inflammatory involvement of the nevrax
  • Express consent to participate in the study
  • Affiliate or beneficiary of a social security scheme

Who cannot take part

  • Patient benefiting from a legal protection measure
  • Pregnant, parturient or breastfeeding woman
  • Absolute or relative contraindication to MRI

Where in France

  • Fondation Ophtalmologique Adolphe de Rothschild (FOR)Paris, FranceContact: Amélie YAVCHITZTaking people

About the trial

What the trial wants to find out

* verification of inclusion and non-inclusion criteria * information and collection of consent * standard imaging protocol prescribed as part of the usual treatment: sagittal T1 and T2 slices after injection of contrast product (Gadolinium), 3D STIR and 3D PSIR sequence. * 3D FGAPSIR sequence at the level of the cervical cord for the duration of the additional sequence is 10 minutes, for a total examination time of 40 minutes (instead of 30 minutes)

Treatments tested

  • MRI

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Evaluation of the Performance of a 3D FGAPSIR Sequence by MRI in the Detection and Characterization of Spinal Cord Injuries in Patients With Multiple Sclerosis
Plain-language title
Tests a new MRI scan for spinal cord lesions in multiple sclerosisGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Record updated
5 January 2026