NCT04920318Recruiting
Enhancing Language Function in Primary Progressive Aphasia
Enhancing Language Function in Primary Progressive Aphasia (PPA) With Transcranial Direct Current Stimulation (tDCS)
Source: ClinicalTrials.gov · Last updated 29 Nov 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study's goal is to use non-invasive brain stimulation (NBS) techniques to treat language impairment associated with Primary Progressive Aphasia (PPA). The purpose of this study is to combine behavioral language intervention with individualized noninvasive brain stimulation techniques, called transcranial direct current stimulation (tDCS) to help the brain reorganize around damage and improve language functions.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 1 Jun 2021
- Start date
- 30 Aug 2021
- Primary completion date
- 30 Dec 2026
- Lead sponsor
- University of Arizona
- Diseases
- Frontotemporal dementia
- NCT number
- NCT04920318
What you commit to
- Study type: Interventional
- Planned participants: 20
- From 30 Aug 2021 to the primary completion date, 30 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- highly magnetizable metallic implants, including certain dental work
- brain surgery in the past
- metallic skull plates or implants
- excessive use of alcohol or drugs
- severe non-linguistic cognitive disturbances impeding language therapy
Other illness
- meeting (Diagnostic and Statistical Manual) DSM-IV criteria for Axis I mood, anxiety, psychotic or substance abuse disorders.
- neurological disorders besides the ones of interest for the study (e.g., epilepsy)
- Parkinson's Disease
- metallic cardiac pumps
- magnetic materials such as surgical clips, implanted electronic perfusion pumps, or any other condition that would preclude proximity to a strong magnetic field.
- severe systemic disease (e.g., renal failure)
- family history of epilepsy or other seizure disorders
- premorbid psychiatric disease affecting communication
Other
- Multiple Sclerosis
- contraindications for MRI
- pacemakers
- valves
- clinically significant claustrophobia
- poor health
- pregnancy
- epileptic activity in the past 12 months
- skin lesions or skull damage
Who the study is looking for
- diagnosed with PPA by neurologist or speech-language pathologist
- speech-language deficit arising from PPA
- native speaker of English Language or equivalent
- adequate vision (normal or corrected to normal)
- adequate hearing
Age in the registry: 45 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Arizona Coordinator of this site? Confirm its status | Tucson | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.