Comparing two latanoprost eye drops in glaucoma patients' eyes
Compares preserved and preservative-free latanoprost eye drops on eye surface cells in glaucoma.
Plain-language title generated from the registry record
Registry title: Effect of Benzalkonium Chloride Preserved and Preservative-free Latanoprost Eye Drops on Conjunctival Goblet Cells
Key facts
- Where
- Glostrup, DenmarkSee the site
- Phase
- Phase 4
Where in Denmark
- RigshospitaletGlostrup, DenmarkNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Copenhagen University Hospital, Rigshospitalet
- Trial code
- NCT04957329EU 2024-512275-12-00
- Record updated
- 18 November 2023
- Original description
a randomized, investigator-blind, interventinal study will compare the effect of benzalkonium-chloride (BAK) preserved and preservative-free (PF) eye drops on conjunctival goblet cells.Read full original descriptionShow less
Department of Ophthalmology, Rigshospitalet-Glostrup Valdemar Hansens Vej 13, 2600 Glostrup, Denmark
a randomized, investigator-blind, interventinal study will compare the effect of benzalkonium-chloride (BAK) preserved and preservative-free (PF) eye drops on conjunctival goblet cells.
Inclusion: Age >18years; Danish speaking; Open angle glaucoma or ocular hypertension; Average intraocular pressure equal to or above 22 mmHg.
Exclusion: history of significant eye diseae (including okular trauma) other than open angle glaucoma and ocular hypertension d. treatment with steroids within the last 3 months from inclusion e. Significant untreated systemic disease such as hypertension, heart failure, diabetes mellitus, stroke, lung disease and autoimmune diseases. Diseases are not reason for exclusion if they are well treated or does not need treatment g. pregnant or breast feeding h. women using unsafe anticonception i. allergy towards trial medication j. patients who cannot cooperate in eye examination k. ocular surface defects l. need for polytherapy in glaucoma treatment.