Studies fluid from the front of the eye in children with retinoblastoma
Collects clear eye fluid and tissue from children with an eye cancer to study it.
Plain-language title generated from the registry record
Registry title: Retinoblastoma Patient Clinical Database and Tissue Repository
Key facts
- Where
- Toronto, CanadaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for children and young people up to 18 years old who have retinoblastoma, an eye cancer, in one or both eyes and are seen at Children's Hospital Los Angeles (CHLA).
- Age
- 0 days to 18 years
- Sex
- All sexes can join.
- Disease stage
- Retinoblastoma in one eye (unilateral) or in both eyes (bilateral).
Main reasons for not taking part
- Patients who came to CHLA only for a second opinion and are not treated there for any reason.
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 0 and 18 years old?
Source: NCT04959097, who can take part
Where in Canada
- The Hospital for Sick Children (Toronto SickKids)Toronto, CanadaContact: Roxanne NoronhaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Children's Hospital Los Angeles
- Trial code
- NCT04959097
- Record updated
- 22 April 2026
- Original description
Retinoblastoma (RB) is a primary eye cancer that forms in the back of the eye of infants and toddlers. Traditionally, RB is diagnosed without a biopsy; tumor can only be studied once an eye has been surgically removed.Read full original descriptionShow less
Retinoblastoma Patient Clinical Database and Tissue Repository
Retinoblastoma (RB) is a primary eye cancer that forms in the back of the eye of infants and toddlers. Traditionally, RB is diagnosed without a biopsy; tumor can only be studied once an eye has been surgically removed.
Given this limitation, we use aqueous humor (AH), the clear fluid in the front of the eye to detect specific markers, or information, that comes from the tumor itself.
Inclusion: All patients, age 0 days to 18 years, with a diagnosis unilateral or bilateral retinoblastoma (RB) seen at CHLA (Children's Hospital Los Angeles).
Exclusion: Patients referred for second opinions only and not treated at CHLA for any reason.