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Testing Hepatitis B Vaccine Booster Doses in Young Adults

Tests hepatitis B vaccine booster doses in young adults lacking protective antibodies against hepatitis B.

Plain-language title generated from the registry record
Registry title: The Immune Responses After Hepatitis B Revaccination Doses in a Young Cohort

Key facts

Where
Taipei, TaiwanSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 20 and 36 years old?

Source: NCT04970836, who can take part

Where in Taiwan

  • Family Medicine, NTUHTaipei, TaiwanTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
National Taiwan University Hospital
Trial code
NCT04970836
Record updated
21 October 2026
Original description
This prospective cohort study aims to provide the evidence-based clinical guide to help decide the revaccination doses of hepatitis B vaccine that the high-risk young adults without hepatitis B seroprotective antibodies (anti-HBs titer<10 mIU/mL) need to take.Read full original descriptionShow less

The Immune Responses After Hepatitis B Revaccination Doses in a Young Cohort

This prospective cohort study aims to provide the evidence-based clinical guide to help decide the revaccination doses of hepatitis B vaccine that the high-risk young adults without hepatitis B seroprotective antibodies (anti-HBs titer<10 mIU/mL) need to take.

Inclusion: The actual age at the time of admission was higher than 20 years old and birth year after 1987; Born in Taiwan and had received a full course of hepatitis B vaccines at least three doses at infant period; Those who have tested negative for hepatitis B surface antibody and surface antigen at baseline; Have never been vaccinated against hepatitis B in childhood and adolescence by questionnaire; Consent to administer 1-2 doses of hepatitis B vaccine according to the assigned group after sharing decision making process; In good health.

Exclusion: Those who were previously allergic to hepatitis B vaccine or its components (such as yeast); Those who have been vaccinated against hepatitis B during childhood and adolescence; Those who have a positive test for hepatitis B surface antibody or a positive test for hepatitis B surface antigen.

ClinicalTrials.gov NCT04970836