Epidiolex in Obsessive Compulsive Disorder and Related Disorders

Who can take part

• Men and women age 18-65
• Primary diagnosis of OCD, Hoarding Disorder, Skin Picking Disorder, Trichotillomania, or Tourette Syndrome
• YBOCS score of at least 18 at baseline
• Ability to understand and sign the consent form

Who cannot take part

• Use of any other psychotropic medication
• Previous treatment with Epidiolex
• Unstable medical illness based on history or clinically significant abnormalities on baseline physical examination or labs
• Past 12-month DSM-5 psychiatric disorder other than OCD
• Cognitive impairment that interferes with the capacity to understand and self-administer medication or provide written informed consent
• Current pregnancy or lactation, or inadequate contraception in women of childbearing potential
• Subjects considered an immediate suicide risk based on the Columbia Suicide Severity Rating Scale (C-SSRS)
• Illegal substance use based on urine toxicology screening
• Initiation of psychological interventions within 3 months of screening