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Taking people in DenmarkPhase 4

Are Carvedilol and Metoprolol Succinate Comparable Treatments in Heart Failure Patients With Reduced Ejection Fraction

Key facts

Where
Odense C, DenmarkSee the site
Phase
Phase 4

Where in Denmark

  • Odense University HospitalOdense C, DenmarkTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Odense University Hospital
Trial code
NCT04996550EU 2022-503010-23-01
Record updated
16 August 2021
Original description
The objective of CROWD-COMPARE is to compare the efficacy of carvedilol and metoprolol succinate on all-cause mortality or first hospitalization for worsening heart failure in patients with heart failure with reduced ejection fraction with an indication for treatment with beta-blockers.Read full original descriptionShow less

Cluster and Registry Trial of the Working Group of Heart Failure in Denmark. Are Carvedilol and Metoprolol Succinate Comparable Treatments in Heart Failure Patients With Reduced Ejection Fraction

The objective of CROWD-COMPARE is to compare the efficacy of carvedilol and metoprolol succinate on all-cause mortality or first hospitalization for worsening heart failure in patients with heart failure with reduced ejection fraction with an indication for treatment with beta-blockers.

Inclusion: Age ≥18 years; NYHA ≥ II; LVEF ≤40%.

Exclusion: No indication for beta-blocker treatment or contraindications for the two for the two study drugs (Carvedilol or metoprolol succinate).

ClinicalTrials.gov NCT04996550 · EU CTIS 2022-503010-23-01