Tests mitochondria infusion into brain vessels during blood flow restoration
Tests healthy mitochondria infused into brain vessels in adults with reduced brain blood flow.
Plain-language title generated from the registry record
Registry title: Autologous Mitochondrial Transplant for Cerebral Ischemia
Key facts
- Where
- Seattle, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 85 years old?
Source: NCT04998357, who can take part
Where in United States
- Harborview Medical CenterSeattle, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Washington
- Trial code
- NCT04998357
- Record updated
- 21 May 2025
- Original description
The investigators propose to infuse healthy autologous mitochondria into cerebral vessels supplying brain tissue experiencing ischemia in patients who undergo standard-of- care endovascular reperfusion therapy.Read full original descriptionShow less
Study Title: Autologous Mitochondrial Transplant for Cerebral Ischemia
The investigators propose to infuse healthy autologous mitochondria into cerebral vessels supplying brain tissue experiencing ischemia in patients who undergo standard-of- care endovascular reperfusion therapy.
Inclusion: Eligible for endovascular thrombectomy to treat acute large vessel occlusion; Eligible for angioplasty (microcatheter-based balloon/mechanical and chemical angioplasty) to treat acute cerebral vasospasm after aneurysmal subarachnoid hemorrhage; Subjects for whom there is likely to be enough time to obtain meaningful consent from patient or legally-authorized representative.
Exclusion: Known mitochondrial disease; Unable to receive a brain MRI scan; Hemodynamically unstable patients in whom standard of care endovascular reperfusion treatment cannot safely be performed or completed.