Tests stem cell infusions and joint injections for rheumatoid arthritis
Tests donor stem cells from umbilical cord or placenta in people with rheumatoid arthritis.
Plain-language title generated from the registry record
Registry title: Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Intravenous Infusion and Intra-Articular Injection for RA
Key facts
- Where
- Athens, GreeceSee the site
- Phase
- Phase 1
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for people with rheumatoid arthritis. They would get stem cells from umbilical cord or placenta, by infusion into a vein and by injection into a joint.
- Sex
- Men and women can join.
- Earlier treatment
- People with a previous organ transplant cannot join.
Main reasons for not taking part
- Active infection
- Active cancer
- Chronic failure of several organs
- Pregnancy
- Previous organ transplant
Read by machine on 9 November 2026.
Where in Greece
- Prodromos Stem Cell InstituteAthens, GreeceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- The Foundation for Orthopaedics and Regenerative Medicine
- Trial code
- NCT05003934
- Record updated
- 20 October 2026
- Original description
This trial will study the safety and efficacy of intravenous infusion and intra-articular injection of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells for the treatment of Rheumatoid ArthritisRead full original descriptionShow less
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Intravenous Infusion and Intra-Articular Injection for the Treatment of Rheumatoid Arthritis
This trial will study the safety and efficacy of intravenous infusion and intra-articular injection of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells for the treatment of Rheumatoid Arthritis
Inclusion: Diagnosis of Rheumatoid Arthritis; Understanding and willingness to sign a written informed consent document.
Exclusion: Continued drug abuse; Previous organ transplant; Active infection; Active cancer; Chronic multisystem organ failure; Medical condition that would (based on the opinion of the investigator) compromise patient's safety; Hypersensitivity to sulfur; Clinically significant Abnormalities on pre-treatment laboratory evaluation; Pregnancy; Pre-menopausal women not using contraception.