Diagnostic Tools to Establish the Presence and Severity of Peripheral Arterial Disease in People With Diabetes
Key facts
- Who runs it
- Imperial College London
- Where
- United Kingdom17 sites in 1 countryChoose a country to see its sites
- Trial code
- Status
- Completed
- People taking part
- 604 people enrolled
- Started
- 14 Mar 2022
- Ended
- 28 Feb 2024
- Type of study
- Observational
- Treatments tested
- Toe Brachial Pressure Index (TBPI)
- Ankle Brachial Pressure Index (ABPI)
- Exercise Ankle Brachial Pressure Index (ABPI)
- Audible handheld Doppler
- Visual handheld Doppler
- Podiatry Ankle Duplex scan (PAD-scan)
- Record updated
- 3 September 2025
Who can take part
- Age
- 18 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 6 criteriaShow less
Who can take part
- Aged ≥18 years
- Known history of diabetes
Who cannot take part
- Known history of PAD intervention
- CTA and MRA contraindications- renal impairment, pregnancy, contrast medium hypersensitivity/allergy, non-compatible implants (MRA only)
- PAD status known on imaging
- Unable to provide appropriate informed consent
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
In the UK there are over 7,000 leg amputations each year because of diabetes. The most important cause of this is poor circulation. The detection of poor circulation in patients with diabetes is difficult. A number of tests exist to detect poor circulation (known as peripheral arterial disease (PAD)). However, there is confusion as to which is the gold standard.
Read full original descriptionShow less
The DM PAD study aims to determine the diagnostic performance of index tests (audible handheld Doppler, visual handheld Doppler, ankle brachial pressure index (ABPI), exercise ABPI and toe brachial pressure index (TBPI)) for the diagnosis of PAD in patients with diabetes as determined by a reference test (CTA or MRA).
The group in the trial
- Participating Centre
To complete all index tests and reference scan
Treatment: Toe Brachial Pressure Index (TBPI), Ankle Brachial Pressure Index (ABPI), Exercise Ankle Brachial Pressure Index (ABPI), Audible handheld Doppler, Visual handheld Doppler, and Podiatry Ankle Duplex scan (PAD-scan)
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Record updated
- 3 September 2025