Tests ischemic postconditioning after clot removal in acute ischemic stroke
Studies a brief blood-flow technique after clot removal in people with stroke.
Plain-language title generated from the registry record
Registry title: Oriental Research AlliaNce of Acute Ischemic Stroke Given Endovascular Treatment
Key facts
- Where
- Shanghai and Zhangzhou, ChinaSee the 2 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 95 years old?
Source: NCT05024292, who can take part
Where in China
- Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai, ChinaTaking people
- Zhangzhou Municipal Hospital of Fujian ProvinceZhangzhou, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
- Trial code
- NCT05024292
- Record updated
- 12 July 2023
- Original description
To determine the safety and efficacy of in situ ischemic postconditioning immediately after successful reperfusion in AIS patients underwnet EVT.Read full original descriptionShow less
Oriental Research Alliance of Acute Ischemic Stroke Given Endovascular Treatment: Technique Feasibility, Safety and Neuroprotective Effects of in Situ Ischemic Postconditioning in Patients Underwent Successful Endovascular Thrombectomy
To determine the safety and efficacy of in situ ischemic postconditioning immediately after successful reperfusion in AIS patients underwnet EVT.
Inclusion: Adult (age ≥ 18 to 95 years) patients with an occlusion of the internal carotid artery or M1 or M2 segment of the middle cerebral artery,; Patients with a score of at least 6 on the National Institutes of Health Stroke Scale (NIHSS) at admission and a score of 0 or 1 on the modified Rankin scale before the onset of stroke; Patients with a score of at least 6 on the Alberta Stroke Program Early CT score (ASPECTS) value; Baseline multimodal-CT imaging, including NCCT, CTA and CTP, performed at the trial-site hospital; The modified thrombolysis in cerebral infarction (mTICI) scale 2b to 3 achieved in the infarct-related artery after the last thrombectomy attempt.
Exclusion: Stoke of large artery atherosclerotic origin or other determined factors (such as dissection) or tandem occlusion; Patients underwent rescue angioplasty or stenting after thrombectomy.