Tests a breathing-synced CT scan before lung cancer radiation
Compares a new breathing-synced scan with usual scan in lung cancer.
Plain-language title generated from the registry record
Registry title: Respiratory Adaptive Computed Tomography: Feasibility Study on Real-Time Gated 4DCT for Lung Cancer Radiotherapy
Key facts
- Where
- Blacktown, AustraliaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with lung cancer who will have radiation therapy that includes a 4DCT planning scan. They get one extra scan on the day of treatment simulation.
- Age
- 18 years or older
- Sex
- Women and men can join.
- Disease stage
- Lung cancer with an indication for radiation therapy.
Main reasons for not taking part
- Pregnant women
- Under 18 years
- Cannot give informed consent
- Treating doctor thinks they could not tolerate the extra time on the CT couch for an extra scan
Read by machine on 12 November 2026.
Where in Australia
- Blacktown HospitalBlacktown, AustraliaContact: Eric HauTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- University of Sydney
- Trial code
- NCT05030207
- Record updated
- 19 May 2026
- Original description
This study does not involve a therapeutic intervention as standard radiation therapy treatment will be prescribed. This study involves one additional 4DCT scan (i.e. the Real-Time Gated 4DCT scan) acquired immediately before or following the conventional 4DCT scan. This will take place on the day of the patient's treatment simulation, as per the current standard of care. The scanning sequence (i.e. conventional first versus gated first) will be randomised.Read full original descriptionShow less
Respiratory Adaptive Computed Tomography: A Pilot Feasibility Study on the Use of Real-Time Gated 4DCT for Lung Cancer Radiation Therapy
This study does not involve a therapeutic intervention as standard radiation therapy treatment will be prescribed. This study involves one additional 4DCT scan (i.e. the Real-Time Gated 4DCT scan) acquired immediately before or following the conventional 4DCT scan. This will take place on the day of the patient's treatment simulation, as per the current standard of care. The scanning sequence (i.e. conventional first versus gated first) will be randomised.
The Real-Time Gated 4DCT is anticipated to take longer than the conventional 4DCT scan, due to its gated (beam-pause) nature. However, upper limits for timing will be implemented in the software, and the scan aborted for highly erratic breathing traces that would not benefit from a Real-Time Gated 4DCT scan.
Inclusion: 18 years or older; Have the ability to give informed consent; A diagnosis of lung cancer with an indication for radiation therapy; Radiation therapy treatment involving the acquisition of a 4DCT scan for treatment planning.
Exclusion: Patients <18 years; Pregnant women; Patients who in the opinion of the treating physician could not tolerate the extra time on the CT couch for an extra scan.