Studies how brain stimulation affects memory in people with memory disorders
Tests intracranial brain stimulation in adults with epilepsy, memory problems or brain injury.
Plain-language title generated from the registry record
Registry title: Amygdala Memory Enhancement
Key facts
- Where
- St Louis, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT05065450, who can take part
Where in United States
- Washington University School of MedicineSt Louis, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Washington University School of Medicine
- Trial code
- NCT05065450
- Record updated
- 17 July 2025
- Original description
The objective is to understand how amygdala activation affects other medial temporal lobe structures to prioritize long-term memories. The project is relevant to disorders of memory and to disorders involving affect and memory, including traumatic brain injury and post-traumatic stress disorder.Read full original descriptionShow less
Mechanisms of Amygdala-Mediated Memory Enhancement in Humans
The objective is to understand how amygdala activation affects other medial temporal lobe structures to prioritize long-term memories. The project is relevant to disorders of memory and to disorders involving affect and memory, including traumatic brain injury and post-traumatic stress disorder.
Inclusion: Must be able to understand and speak English; Able to provide informed consent; Diagnosed with epilepsy; Scheduled to undergo long-term intra-cranial video monitoring for seizure onset localization; Must be implanted with intracranial depth electrodes to the left or right amygdala, hippocampus, and parahippocampal/perirhinal cortices.
Exclusion: Not diagnosed with epilepsy; Unable to understand and speak English; Unable to provide informed consent.