NCT05079399Recruiting
Biomarker of Diabetic Retinopathy
Source: ClinicalTrials.gov · Last updated 23 Jul 2026
Brief summary (registry, in English)
Diabetic retinopathy (DR) is a complication of diabetes in which blood vessels supplying blood to the back of the eye (retina) are dysfunctional. This can lead to an improper supply of oxygen and nutrients to the retinal tissue, or it may trigger the formation of new blood vessels in response to the oxygen/nutrient deficiency. Ultimately affecting the normal vision. There is no known marker that will provide information on the health status of retinal blood vessels. Using highly specialized cells in the blood, this study will try to discover a marker of DR.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 192 (estimated)
- First submitted
- 11 Sept 2021
- Start date
- Jan 2022
- Primary completion date
- Jun 2027
- Lead sponsor
- Indiana University
- Diseases
- Diabetic eye disease
- NCT number
- NCT05079399
What you commit to
- Study type: Observational
- Planned participants: 192
- From Jan 2022 to the primary completion date, Jun 2027
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous or current malignancy
- History of previous vitrectomy
Other illness
- Acute or chronic infection (HIV, hepatitis B or C, tuberculosis)
- History of organ transplantation
Age
- Subjects with a history of age-related macular degeneration age-related macular degeneration (AMD), glaucoma, uveitis, and branched or central vein occlusion.
Other
- Cerebral vascular accident or cerebral vascular procedure
- Current pregnancy
- Presence of a graft (to avoid any effect of the graft)
Who the study is looking for
- Ability to cooperate with imaging procedures.
- Health status: established type 2 diabetes
- No history of panretinal photocoagulation (PRP)
- No history of treatment with intravitreal agents for past 12 months
Age in the registry: 18 years to - · Sex: All
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Spring Mill Clinic Coordinator of this site? Confirm its status | Carmel | United States | Recruiting |
| Glick Eye Institute Coordinator of this site? Confirm its status | Indianapolis | United States | Recruiting |
| Eskenazi Eye Clinic Coordinator of this site? Confirm its status | Indianapolis | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.