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Walking Recovery Training After Stroke

Tests high-intensity stepping training in adults recovering from stroke.

Plain-language title generated from the registry record
Registry title: Locomotor Recovery and Compensation Post-stroke (LRC)

Key facts

Where
Indianapolis, United StatesSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 85 years old?

Source: NCT05081713, who can take part

Where in United States

  • Rehabilitation Hospital of IndianaIndianapolis, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Indiana University
Trial code
NCT05081713
Record updated
5 March 2026
Original description
The proposed research will characterize of the time course of neurological and locomotor recovery as well as development of compensatory strategies throughout sub-acute and chronic phases post stroke. In addition, we will also investigate the extent to which measures of recovery and compensation are malleable and can be altered with specific interventions in both the early and late stages post-stroke. Delineation of the time course of development and magnitude of patterns of recovery and compensation should result in alternative predictive "rules' regarding how patients early post-stroke could recovery functional and neurological function.Read full original descriptionShow less

Locomotor Recovery and Compensation Post-stroke (LRC)

The proposed research will characterize of the time course of neurological and locomotor recovery as well as development of compensatory strategies throughout sub-acute and chronic phases post stroke. In addition, we will also investigate the extent to which measures of recovery and compensation are malleable and can be altered with specific interventions in both the early and late stages post-stroke. Delineation of the time course of development and magnitude of patterns of recovery and compensation should result in alternative predictive "rules' regarding how patients early post-stroke could recovery functional and neurological function.

Inclusion: individuals early post-stroke (<15-30 days); first ever stroke; unilateral hemiparesis; currently receiving inpatient rehabilitation; ability to follow 1-step commands; provision of informed consent; medical clearance from the rehabilitation physician to participate. \.

Exclusion: other orthopedic or neurological disorder that limited walking prior to stroke; uncontrolled cardiovascular, metabolic or respiratory disease that limits exercise participation (e.g., congestive heart failure, resting blood pressure > 200/110 mmHg, uncontrolled diabetes, end-stage renal disease); absolute criteria for termination of exercise testing during initial and repeated ECG testing during graded exercise testing using ACSM guidelines .

ClinicalTrials.gov NCT05081713