Substance Use Treatment and Recovery Team
Key facts
- Who runs it
- Cedars-Sinai Medical Center
- Where
- Albuquerque, Los Angeles, and Springfield, United StatesSee the 3 sites
- Trial code
- Status
- Completed
- People taking part
- 325 people enrolled
- Started
- 11 Nov 2021
- Ended
- 19 Dec 2023
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Substance Use Treatment and Recovery Team (START)
- Record updated
- 23 January 2025
Who can take part
- Age
- 18 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 8 criteriaShow less
Who can take part
- Admitted to an inpatient bed at Cedars-Sinai Medical Center (CSMC),University of New Mexico Hospital (UNM), or Baystate Health (BH)
- Age 18 and older
- Have a probable OUD diagnosis, defined by scores of > 3 on the opioid section of the Alcohol, Smoking, and Substance Involvement Screening test (ASSIST)
- Speaks English or Spanish as primary language
- Willing to participate in follow-up calls and interview by telephone and able to provide contact information for follow-up calls
- Able to provide informed consent
Who cannot take part
- Currently receiving FDA-approved medication treatment for an opioid use disorder
- < 6 months life expectancy
Where in United States
- University of New Mexico HospitalAlbuquerque, United States
- Cedars-Sinai Medical CenterLos Angeles, United States
- Baystate Medical CenterSpringfield, United States
About the trial
What the trial wants to find out
This study is a multi-site, randomized pragmatic trial being conducted at three diverse sites. The study, called the Substance Use Treatment and Recovery Team (START), will evaluate whether a collaborative care team increases the use of two interventions-medication for opioid use disorder (MOUD), and opioid use disorder (OUD) focused discharge planning-among hospitalized patients with OUD, and improves linkage to follow-up care relative to usual care. The START consists of an addiction medicine specialist and a care manager who will use evidence-based tools to decrease barriers to MOUD and engage patients with post-discharge OUD care. A total of 414 patients will be randomized from Cedars-Sinai Medical Center in Los Angeles, the University of New Mexico Hospital in Albuquerque, and Baystate Health in Springfield, Massachusetts to receive either START or usual care, stratifying by prior MOUD exposure and site.
The 2 groups in the trial
- Substance Use Treatment and Recovery Team (START)Existing treatment, for comparison
The intervention is administered to participants in this arm. Participants in this arm will work with the Substance Use Treatment and Recovery Team (START), a collaborative care team for inpatients with opioid use disorder.
- Usual CareNo study treatment, for comparison
Usual care for people with opioid use disorder.
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Publications
- Hospital Addiction Consultation Service and Opioid Use Disorder Treatment: The START Randomized Clinical Trial.JAMA internal medicine, 2025
- The Substance Use Treatment and Recovery Team (START) study: protocol for a multi-site randomized controlled trial evaluating an intervention to improve initiation of medication and linkage to post-discharge care for hospitalized patients with opioid use disorder.Addiction science & clinical practice, 2022
- Record updated
- 23 January 2025