Tests brain stimulation with speech therapy for stroke-related language loss
Tests cerebellar stimulation added to language therapy in adults with stroke-related aphasia.
Plain-language title generated from the registry record
Registry title: Cerebellar Stimulation for Aphasia Rehabilitation
Key facts
- Where
- Baltimore, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 99 years old?
Source: NCT05093673, who can take part
Where in United States
- Johns Hopkins HospitalBaltimore, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Johns Hopkins University
- Trial code
- NCT05093673
- Record updated
- 20 March 2026
- Original description
The optimal site of neuromodulation for post-stroke aphasia has yet to be established. This study will investigate whether multiple sessions of cerebellar transcranial direct current stimulation (tDCS) boosts language therapy in helping people recover from aphasia as well as predict who is likely to respond to cerebellar tDCS.Read full original descriptionShow less
Cerebellar Stimulation for Aphasia Rehabilitation
The optimal site of neuromodulation for post-stroke aphasia has yet to be established. This study will investigate whether multiple sessions of cerebellar transcranial direct current stimulation (tDCS) boosts language therapy in helping people recover from aphasia as well as predict who is likely to respond to cerebellar tDCS.
Inclusion: Chronic ischemic or hemorrhagic left hemisphere stroke; Fluent speaker of English by self-report; Age 18 or older; 6 months post onset of stroke; Diagnosis of aphasia and naming impairment using the Western Aphasia Battery-Revised.
Exclusion: Previous neurological disorder (other than stroke) affecting the brain, or any other neurodegenerative disorder or psychiatric disorder; Seizures during the previous 6 months; Use of medications that lower the seizure threshold (e.g., methylphenidate); History of brain surgery or any metal in the head; Individuals with severe claustrophobia, cardiac pacemakers or ferromagnetic implants, and pregnant women will be excluded from the MRI portion of the study; Lesion in the right cerebellum; Uncorrected visual loss or hearing loss by self-report; Use of N-methyl-D-aspartate (NMDA) antagonists (e.g., memantine); Severely impaired auditory comprehension (lower than 2 on the Comprehension subscore on the Western Aphasia Battery-Revised); Severely limited verbal output (lower than 2 on the Spontaneous Speech rating scale on the Western Aphasia Battery-Revised).