Studies skin bacteria in atopic dermatitis patients receiving systemic therapy
Observes how skin bacteria change in adults with eczema on whole-body treatment.
Plain-language title generated from the registry record
Registry title: Microbiome in Atopic Dermatitis Under Systemic Therapy
Key facts
- Where
- Berlin, GermanySee the site
Where in Germany
- Dpt of Dermatology and Allergology, Charité - Universitätsmedizin BerlinBerlin, GermanyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Charite University, Berlin, Germany
- Trial code
- NCT05099315
- Record updated
- 22 October 2026
- Original description
The skin microbiome plays a role in the pathogenesis of atopic dermatitis. However, it is unclear whether the range of microbiota on the skin is the cause or consequence of atopic skin inflammation.Read full original descriptionShow less
Identification of Skin-associated Microbiota in Atopic Dermatitis Patients Undergoing Systemic Therapy
The skin microbiome plays a role in the pathogenesis of atopic dermatitis. However, it is unclear whether the range of microbiota on the skin is the cause or consequence of atopic skin inflammation.
The influence of new systemic therapies for the treatment of moderate to severe atopic dermatitis (such as biologics or Janus kinase inhibitors) on the skin microbiome is largely unknown.
The main aim of this scientific exploratory study is to investigate whether and how the skin microbiome changes in patients with moderate to severe atopic dermatitis during systemic therapy. This not only allows new hypotheses to be generated on the pathogenesis of atopic dermatitis, but also new objective scales for the severity of atopic dermatitis can be developed.
Inclusion: Patients with moderate to severe atopic dermatitis; Indication for systemic therapy.
Exclusion: Patients under 18 years of age upon introducing systemic therapy; Pregnant and lactating women.