Studies gut bacteria imbalance and stroke risk in young adults
Observes gut bacteria in young adults with ischemic or hemorrhagic stroke.
Plain-language title generated from the registry record
Registry title: Correlation Between Intestinal Microecology Imbalance and Stroke in Young Adults
Key facts
- Where
- Shanghai, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 45 years old?
Source: NCT05113043, who can take part
Where in China
- Shanghai 6th People's HospitalShanghai, ChinaNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Shanghai 6th People's Hospital
- Trial code
- NCT05113043
- Record updated
- 23 April 2026
- Original description
The relationship between the intestinal microecology and stroke has become a research hotspot in neurology field today. Maintaining the balance of the intestinal microbiota are expected to bring new breakthroughs for prevention and treatment of stroke. In recent years, stroke in young adults has an increasing incidence and a considerable socioeconomic impact because of high disability rate and health-care costs. So there is an urgent need to explore the role and mechanism of intestinal microecology imbalance in stroke, especially in the development and prognosis of stroke in young people. This study aims to use multi-omics technologies, including microbial diversity, metagenomics and metabonomics, to reveal the characteristics of intestinal flora in young stroke patients, identify biomarkers for predicting outcome after stroke and early detection of young people at high risk of stroke, and to further explore the role of gut-brain axis in the pathogenesis of stroke.Read full original descriptionShow less
Research on Correlation Between Intestinal Microecology Imbalance and the Risk and Prognosis of Stroke in Young Adults
The relationship between the intestinal microecology and stroke has become a research hotspot in neurology field today. Maintaining the balance of the intestinal microbiota are expected to bring new breakthroughs for prevention and treatment of stroke. In recent years, stroke in young adults has an increasing incidence and a considerable socioeconomic impact because of high disability rate and health-care costs. So there is an urgent need to explore the role and mechanism of intestinal microecology imbalance in stroke, especially in the development and prognosis of stroke in young people. This study aims to use multi-omics technologies, including microbial diversity, metagenomics and metabonomics, to reveal the characteristics of intestinal flora in young stroke patients, identify biomarkers for predicting outcome after stroke and early detection of young people at high risk of stroke, and to further explore the role of gut-brain axis in the pathogenesis of stroke.
Inclusion: Clinical diagnosis of acute ischemic or hemorrhagic stroke; Admission within 12 hours; Aged 18-45 years.
Exclusion: History of neurological diseases, myocardial infarction, renal and hepatic abnormalities and metabolic diseases; Combined with tumors, inflammatory bowel disease and other digestive system diseases; Combined with serious life-threatening diseases or condition; Any antibiotics, probiotics or prebiotic treatment within 3 months; Deteriorate and die before collecting faecal samples.