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CompletedNo phase

Embodied Virtual Reality for Chronic Pain

Key facts

Who runs it
University of Zurich
Where
Switzerland1 site in 1 countryChoose a country to see its sites
Trial code
Status
Completed
People taking part
29 people enrolled
Started
31 May 2021
Ended
31 Aug 2024
Type of study
Interventional, 2 groupsOne group gets no study treatment, for comparison.
Treatments tested
  • Embodied virtual reality
Record updated
18 October 2024

Who can take part

Age
18 years to 80 years
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

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Who can take part

  • Written informed consent by the participants
  • Presence of one of the following chronic pain conditions of the upper limbs:; osteoarthritis (OA), complex regional pain syndrome (CRPS)

Who cannot take part

  • Inability to follow study procedures, e.g., due to language problems, psychological disorders, dementia, etc. of the participant
  • High risk populations for Covid-19 (i.e., high blood pressure, chronic respiratory condition, diabetes, presence of autoimmune disease, cardiovascular disease, presence of cancer)
  • Extreme motion sickness, nausea, or dizziness to the virtual simulations
  • Currently pregnant or breastfeeding women

This trial has no sites in United States.

It has sites in one country. Choose a country to see its sites.

About the trial

What the trial wants to find out

Virtual reality creates interactive, multimodal sensory stimuli that have demonstrated considerable success in reducing pain. Much research so far has focused on VR's ability to shift patients' attention away from pain; however, these methods provide only transient relief through means of distraction and therefore do not offer long-term analgesic remediation. An alternative and promising approach is to utilize VR as an embodied simulation technique, where virtual body illusions are employed as tools to improve body perception and produce potentially more enduring analgesia.

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Disturbances in body perception (i.e., alterations in the way the body is perceived) are increasingly acknowledged as a pertinent feature of chronic pain, and include aberrations in perceived shape, size, or color that differ from objective assessment. The degree of body perception distortion positively correlates with pain, and prior interventions have evinced that treatments aimed at reducing body perception distortions correspondingly ameliorate pain. Several recent experimental research studies have demonstrated the analgesic efficacy of body illusions in a range of pain conditions.

Immersive VR multisensory feedback training signifies a promising new avenue for the potential treatment of chronic pain by supporting the design of targeted virtual environments to alter (distorted) body perceptions. Various illusions have been described to alter pain perception; however, they. Have not been directly compared to each other. The multimodal stimulus control of VR enables physical-to-virtual body transfer illusions, resulting in the feeling that the virtual body is one's own. These virtual body illusions can modulate body perception with ease and could therefore be used to alter the perceived properties of pain, consequently utilizing a virtual avatar to specifically shape interactive processing between central and peripheral mechanisms.

The 2 groups in the trial

  • Bodily illusionsTreatment being tested

    Participants in the experimental group see a bodily illusion applied to their embodied virtual avatar.

    Treatment: Embodied virtual reality

  • No bodily illusionsNo study treatment, for comparison

    Participants in the control group embody a virtual avatar, but without bodily illusions

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Record updated
18 October 2024